Cited 37 times in
Combined therapy of corticosteroid and azathioprine in hypertrophic cranial pachymeningitis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박수철 | - |
dc.date.accessioned | 2019-11-11T05:07:42Z | - |
dc.date.available | 2019-11-11T05:07:42Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 0014-3022 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/171632 | - |
dc.description.abstract | Hypertrophic cranial pachymeningitis (HCP) is a rare inflammatory disease of unknown origin in which recurrence is frequently observed in spite of the initial response to steroid therapy. Three patients, 1 man and 2 women, aged 63, 66, and 67 years, with severe intractable headache were evaluated by brain MRI. All patients were initially given prednisolone (60 mg/day, oral) or dexamethasone (20 mg/day, i.v.), and followed by long-term (at least 1 year) azathioprine therapy. All patients were evaluated by follow-up laboratory tests and brain MRI study, and completed the 2-year follow-up period. Symptoms including headache were initially improved with corticosteroid therapy, but patients became steroid-dependent. Azathioprine administration in these steroid-dependent patients permitted the complete cessation of corticosteroid and led to the clinical and radiological recovery. In conclusion, initial high-dose corticosteroid administration followed by long-term azathioprine therapy may be the ideal treatment of HCP at present. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Karger | - |
dc.relation.isPartOf | European Neurology | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adrenal Cortex Hormones/administration & dosage* | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Azathioprine/administration & dosage* | - |
dc.subject.MESH | Disease Progression | - |
dc.subject.MESH | Drug Therapy, Combination | - |
dc.subject.MESH | Dura Mater/drug effects | - |
dc.subject.MESH | Dura Mater/pathology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertrophy/drug therapy* | - |
dc.subject.MESH | Hypertrophy/pathology | - |
dc.subject.MESH | Hypertrophy/physiopathology | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Meningitis/drug therapy* | - |
dc.subject.MESH | Meningitis/pathology | - |
dc.subject.MESH | Meningitis/physiopathology | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Secondary Prevention | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Combined therapy of corticosteroid and azathioprine in hypertrophic cranial pachymeningitis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학교실) | - |
dc.contributor.googleauthor | Choi I.S. | - |
dc.contributor.googleauthor | Park S.C. | - |
dc.contributor.googleauthor | Jung Y.K. | - |
dc.contributor.googleauthor | Lee S.S. | - |
dc.identifier.doi | 10.1159/000008235 | - |
dc.contributor.localId | A01543 | - |
dc.relation.journalcode | J00849 | - |
dc.identifier.eissn | 1421-9913 | - |
dc.identifier.pmid | 11096216 | - |
dc.identifier.url | https://www.karger.com/Article/FullText/8235 | - |
dc.subject.keyword | Hypertrophic pachymeningitis | - |
dc.subject.keyword | Dura mater | - |
dc.subject.keyword | Corticosteroid | - |
dc.subject.keyword | Azathioprine | - |
dc.contributor.alternativeName | Park, Soo Chul | - |
dc.contributor.affiliatedAuthor | 박수철 | - |
dc.citation.volume | 44 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 193 | - |
dc.citation.endPage | 198 | - |
dc.identifier.bibliographicCitation | European Neurology, Vol.44(4) : 193-198, 2000 | - |
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