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A novel lumen-apposing metal stent with an anti-reflux valve for endoscopic ultrasound-guided drainage of pseudocysts and walled-off necrosis: A pilot study

DC FieldValueLanguage
dc.contributor.author박승우-
dc.contributor.author박정엽-
dc.contributor.author방승민-
dc.contributor.author송시영-
dc.contributor.author이희승-
dc.contributor.author정문재-
dc.date.accessioned2019-10-28T02:03:17Z-
dc.date.available2019-10-28T02:03:17Z-
dc.date.issued2019-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/171461-
dc.description.abstractBACKGROUND: Pancreatic pseudocysts (PC) and walled-off necrosis (WON) are common complications of severe pancreatitis. Endoscopic ultrasound (EUS)-guided drainage has replaced surgery as the standard treatment for PC/WON. We developed a novel lumen-apposing metal stent (LAMS) with an anti-reflux valve to prevent infectious complications caused by food reflux into the cyst cavity. This retrospective study investigated the efficacy and safety of EUS-guided drainage using this LAMS. METHODS: We investigated and compared the treatment outcomes and complications rates between EUS-guided drainage using a novel LAMS (n = 10) versus plastic stents (n = 18) from December 2013 to October 2016. Technical success was defined as successful stent placement without immediate complications. Clinical success was defined as resolution of the PC/WON and disappearance of symptoms. RESULTS: Among 10 patients in LAMS group, 4 patients had complicated PC and 6 patients had WON. In the plastic stent group, 15 and 3 patients had PC and WON, respectively. The median fluid collection size before treatment was 82.5 (interquartile range [IQR], 60.75-118.25) mm and 92.0 (IQR, 75.75-130.25) mm in the LAMS and plastic stent groups, respectively. There were no statistically significant differences in technical success rates (90% vs. 94.4%; p = 0.999), clinical success rates (80% vs. 77.8%; p = 0.999), and complication rates (20% vs. 27.8%; p = 0.999) between the two groups. CONCLUSIONS: Treatment outcomes of EUS-guided drainage using a novel LAMS were feasible despite the significantly high proportion of WON. The LAMS allowed acceptable treatment outcomes for EUS-guided drainage.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherPublic Library of Science-
dc.relation.isPartOfPLoS One-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleA novel lumen-apposing metal stent with an anti-reflux valve for endoscopic ultrasound-guided drainage of pseudocysts and walled-off necrosis: A pilot study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorIn Rae Cho-
dc.contributor.googleauthorMoon Jae Chung-
dc.contributor.googleauthorJung Hyun Jo-
dc.contributor.googleauthorHee Seung Lee-
dc.contributor.googleauthorJeong Youp Park-
dc.contributor.googleauthorSeungmin Bang-
dc.contributor.googleauthorSeung Woo Park-
dc.contributor.googleauthorSi Young Song-
dc.identifier.doi10.1371/journal.pone.0221812-
dc.contributor.localIdA01551-
dc.contributor.localIdA01647-
dc.contributor.localIdA01647-
dc.contributor.localIdA01786-
dc.contributor.localIdA01786-
dc.contributor.localIdA02035-
dc.contributor.localIdA02035-
dc.contributor.localIdA03349-
dc.contributor.localIdA03349-
dc.contributor.localIdA03602-
dc.contributor.localIdA03602-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid31483821-
dc.contributor.alternativeNamePark, Seung Woo-
dc.contributor.affiliatedAuthor박승우-
dc.contributor.affiliatedAuthor박정엽-
dc.contributor.affiliatedAuthor박정엽-
dc.contributor.affiliatedAuthor방승민-
dc.contributor.affiliatedAuthor방승민-
dc.contributor.affiliatedAuthor송시영-
dc.contributor.affiliatedAuthor송시영-
dc.contributor.affiliatedAuthor이희승-
dc.contributor.affiliatedAuthor이희승-
dc.contributor.affiliatedAuthor정문재-
dc.contributor.affiliatedAuthor정문재-
dc.citation.volume14-
dc.citation.number9-
dc.citation.startPagee0221812-
dc.identifier.bibliographicCitationPLoS One, Vol.14(9) : e0221812, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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