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Clinical Value of Lymph Node Ratio Integration with the 8th Edition of the UICC TNM Classification and 2015 ATA Risk Stratification Systems for Recurrence Prediction in Papillary Thyroid Cancer

DC FieldValueLanguage
dc.contributor.author강상욱-
dc.contributor.author남기현-
dc.contributor.author이잔디-
dc.contributor.author이초록-
dc.contributor.author정웅윤-
dc.contributor.author정종주-
dc.contributor.author조영석-
dc.contributor.author김광순-
dc.date.accessioned2019-10-28T02:00:58Z-
dc.date.available2019-10-28T02:00:58Z-
dc.date.issued2019-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/171446-
dc.description.abstractRecently, the 2015 American Thyroid Association (ATA) risk stratification and the 8th edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) TNM staging system were released. This study was conducted to assess the clinical value of the lymph node ratio (LNR) as a predictor of recurrence when integrated with these newly released stratification systems, and to compare the predictive accuracy of the modified systems with that of the newly released systems. The optimal LNR threshold value for predicting papillary thyroid cancer (PTC) recurrence was 0.17857 using the Contal and O'Quigley method. The 8th edition of the AJCC/UICC TNM staging system with the LNR and the 2015 ATA risk stratification system with the LNR were significant predictors of recurrence. Furthermore, calculation of the proportion of variance explained (PVE), the Akaike information criterion (AIC), Harrell's c index, and the incremental area under the curve (iAUC) revealed that the 8th edition of the TNM staging system with the LNR, and the 2015 ATA risk stratification system with the LNR, showed the best predictive performance. Integration of the LNR with the TNM staging and the ATA risk stratification systems should improve prediction of recurrence in patients with PTC.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfScientific Reports-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleClinical Value of Lymph Node Ratio Integration with the 8th Edition of the UICC TNM Classification and 2015 ATA Risk Stratification Systems for Recurrence Prediction in Papillary Thyroid Cancer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학교실)-
dc.contributor.googleauthorJandee Lee-
dc.contributor.googleauthorSeul Gi Lee-
dc.contributor.googleauthorKwangsoon Kim-
dc.contributor.googleauthorSeung Hyuk Yim-
dc.contributor.googleauthorHaengrang Ryu-
dc.contributor.googleauthorCho Rok Lee-
dc.contributor.googleauthorSang Wook Kang-
dc.contributor.googleauthorJong Ju Jeong-
dc.contributor.googleauthorKee-Hyun Nam-
dc.contributor.googleauthorWoong Youn Chung-
dc.contributor.googleauthorYoung Suk Jo-
dc.identifier.doi10.1038/s41598-019-50069-4-
dc.contributor.localIdA00032-
dc.contributor.localIdA01245-
dc.contributor.localIdA01245-
dc.contributor.localIdA03066-
dc.contributor.localIdA03066-
dc.contributor.localIdA03256-
dc.contributor.localIdA03256-
dc.contributor.localIdA03674-
dc.contributor.localIdA03674-
dc.contributor.localIdA03722-
dc.contributor.localIdA03722-
dc.contributor.localIdA03853-
dc.contributor.localIdA03853-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid31527831-
dc.contributor.alternativeNameKang, Sang Wook-
dc.contributor.affiliatedAuthor강상욱-
dc.contributor.affiliatedAuthor남기현-
dc.contributor.affiliatedAuthor남기현-
dc.contributor.affiliatedAuthor이잔디-
dc.contributor.affiliatedAuthor이잔디-
dc.contributor.affiliatedAuthor이초록-
dc.contributor.affiliatedAuthor이초록-
dc.contributor.affiliatedAuthor정웅윤-
dc.contributor.affiliatedAuthor정웅윤-
dc.contributor.affiliatedAuthor정종주-
dc.contributor.affiliatedAuthor정종주-
dc.contributor.affiliatedAuthor조영석-
dc.contributor.affiliatedAuthor조영석-
dc.citation.volume9-
dc.citation.number1-
dc.citation.startPage13361-
dc.identifier.bibliographicCitationScientific Reports, Vol.9(1) : 13361, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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