Cited 46 times in
A Diet Rich in Vegetables and Fruit and Incident CKD: A Community-Based Prospective Cohort Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강신욱 | - |
dc.contributor.author | 박정탁 | - |
dc.contributor.author | 유태현 | - |
dc.contributor.author | 지종현 | - |
dc.contributor.author | 한승혁 | - |
dc.date.accessioned | 2019-10-28T02:00:46Z | - |
dc.date.available | 2019-10-28T02:00:46Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 0272-6386 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/171445 | - |
dc.description.abstract | RATIONALE & OBJECTIVE: A diet rich in vegetables and fruit can lower blood pressure and may reduce cardiovascular risk. However, the association between this dietary pattern and incident chronic kidney disease in the general population is unknown. STUDY DESIGN: A community-based prospective cohort study. SETTING & PARTICIPANTS: 9,229 study participants with normal kidney function from the Korean Genome and Epidemiology Study database. PREDICTORS: Daily consumption of nonfermented and fermented vegetables and fruit classified into tertiles based on a validated semiquantitative food-frequency questionnaire. OUTCOMES: Incident occurrence of estimated glomerular filtration rate (eGFR) < 60mL/min/1.73m2, incident proteinuria (≥1+ by dipstick test), and repeated measures of estimated net endogenous acid production. ANALYTICAL APPROACH: Multivariable cause-specific hazards model to assess the association of vegetable and fruit intake with incident chronic kidney disease. RESULTS: During a mean follow-up of 8.2 years, 1,741 (21.9/1,000 person-years [PY]) participants developed eGFRs < 60mL/min/1.73m2. Incident eGFR < 60mL/min/1.73m2 occurred less frequently with higher intake of nonfermented vegetables, occurring at rates of 22.8/1,000 PY, 22.7/1,000 PY, and 20.1/1,000 PY for the lowest, middle, and highest tertiles, respectively; P for trend < 0.001. The incidence of proteinuria was also lower in the middle and highest tertiles. In a multivariable cause-specific hazards model, the highest tertile of nonfermented vegetable intake was associated with 14% lower risk for incident eGFR < 60mL/min/1.73m2 than the lowest tertile. The highest tertile was also associated with 32% lower risk for proteinuria than the lowest tertile. There were no associations of fermented vegetable and fruit intake with incidence of eGFR < 60mL/min/1.73m2. However, the highest tertiles of both fermented vegetable and fruit intake were associated with 14% and 45% lower risks for incident proteinuria compared with the lowest tertiles (both P < 0.001). During follow-up, estimated net endogenous acid production increased in the lowest tertile of intake of nonfermented or fermented vegetables and fruit, whereas it decreased in the highest tertile. LIMITATIONS: Self-reported dietary intake, single ethnicity population. CONCLUSIONS: A diet rich in vegetables and fruit may reduce the risk for kidney disease. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | W.B. Saunders | - |
dc.relation.isPartOf | American Journal of Kidney Diseases | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | A Diet Rich in Vegetables and Fruit and Incident CKD: A Community-Based Prospective Cohort Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jong Hyun Jhee | - |
dc.contributor.googleauthor | Youn Kyung Kee | - |
dc.contributor.googleauthor | Jung Tak Park | - |
dc.contributor.googleauthor | Tae-Ik Chang | - |
dc.contributor.googleauthor | Ea Wha Kang | - |
dc.contributor.googleauthor | Tae-Hyun Yoo | - |
dc.contributor.googleauthor | Shin-Wook Kang | - |
dc.contributor.googleauthor | Seung Hyeok Han | - |
dc.identifier.doi | 10.1053/j.ajkd.2019.02.023 | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A01654 | - |
dc.contributor.localId | A02526 | - |
dc.contributor.localId | A03970 | - |
dc.contributor.localId | A04304 | - |
dc.relation.journalcode | J00089 | - |
dc.identifier.eissn | 1523-6838 | - |
dc.identifier.pmid | 31040089 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0272638619306626 | - |
dc.subject.keyword | Vegetable | - |
dc.subject.keyword | chronic kidney disease (CKD) | - |
dc.subject.keyword | diet | - |
dc.subject.keyword | eating patterns | - |
dc.subject.keyword | estimated glomerular filtration rate (eGFR) | - |
dc.subject.keyword | fermented vegetable | - |
dc.subject.keyword | food choices | - |
dc.subject.keyword | fruit | - |
dc.subject.keyword | incident CKD | - |
dc.subject.keyword | modifiable risk factor | - |
dc.subject.keyword | non-fermented vegetable | - |
dc.subject.keyword | proteinuria | - |
dc.subject.keyword | reduced eGFR | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | 강신욱 | - |
dc.contributor.affiliatedAuthor | 박정탁 | - |
dc.contributor.affiliatedAuthor | 유태현 | - |
dc.contributor.affiliatedAuthor | 지종현 | - |
dc.contributor.affiliatedAuthor | 한승혁 | - |
dc.citation.volume | 74 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 491 | - |
dc.citation.endPage | 500 | - |
dc.identifier.bibliographicCitation | American Journal of Kidney Diseases, Vol.74(7) : 491-500, 2019 | - |
dc.identifier.rimsid | 63216 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.