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Effect of Cardiac Rehabilitation on Outcomes in Patients with ST-Elevation Myocardial Infarction

DC FieldValueLanguage
dc.contributor.author홍성진-
dc.date.accessioned2019-09-20T07:37:08Z-
dc.date.available2019-09-20T07:37:08Z-
dc.date.issued2019-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/170977-
dc.description.abstractPURPOSE: Whether cardiac rehabilitation (CR) improves clinical outcomes in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) with drug-eluting stents (DESs) has not been thoroughly evaluated. Moreover, few studies have sought to identify patients who would benefit most from CR among STEMI patients. MATERIALS AND METHODS: Consecutively, 265 STEMI patients who underwent primary PCI with implantation of DESs and follow-up angiography were examined. Seventy-six patients (30%) who received CR were assigned to the CR+ group. Another 178 patients (70%) who did not participate in CR were assigned to the CR- group. Second generation DESs were implanted in 238 (94%) patients. RESULTS: Major adverse cardiovascular events (MACEs), including death, myocardial infarction, and revascularization, were compared. The CR+ group tended to have lower MACE than the CR- group at 3 years, although the difference was not statistically significant (9.9% vs. 18.3%, hazard ratio=0.54, p=0.138). Subgroup analysis revealed a significant interaction according to CR and preprocedural thrombolysis in myocardial infarction (TIMI) flow (p value for interaction=0.011). In patients with low preprocedural TIMI flow (TIMI flow ≤1, n=161), those in the CR+ group had significantly lower MACE than those in the CR- group (p=0.005), whereas MACE was not different among patients with higher TIMI flow (TIMI flow ≥2, n=93). CONCLUSION: CR including exercise training was associated with lower MACE, particularly in patients with lower preprocedural TIMI flow during primary PCI for STEMI in the current DES era.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYonsei Medical Journal-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHCardiac Rehabilitation*-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHST Elevation Myocardial Infarction/diagnostic imaging-
dc.subject.MESHST Elevation Myocardial Infarction/rehabilitation*-
dc.subject.MESHTreatment Outcome-
dc.titleEffect of Cardiac Rehabilitation on Outcomes in Patients with ST-Elevation Myocardial Infarction-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorHye Young Lee-
dc.contributor.googleauthorSung-Jin Hong-
dc.contributor.googleauthorIn Hyun Jung-
dc.contributor.googleauthorGwang Sil Kim-
dc.contributor.googleauthorYoung Sup Byun-
dc.contributor.googleauthorByung Ok Kim-
dc.identifier.doi10.3349/ymj.2019.60.6.535-
dc.contributor.localIdA04403-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid31124336-
dc.subject.keywordCardiac rehabilitation-
dc.subject.keyworddrug eluting stent-
dc.subject.keywordmyocardial infarction-
dc.contributor.alternativeNameHong, Sung Jin-
dc.contributor.affiliatedAuthor홍성진-
dc.citation.volume60-
dc.citation.number6-
dc.citation.startPage535-
dc.citation.endPage541-
dc.identifier.bibliographicCitationYonsei Medical Journal, Vol.60(6) : 535-541, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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