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Prevalence and Characteristics of Restless Legs Syndrome in Korean Adults: A Study in Two Independent Samples of the General Population

DC FieldValueLanguage
dc.contributor.author주민경-
dc.contributor.author김원주-
dc.date.accessioned2019-09-20T07:35:44Z-
dc.date.available2019-09-20T07:35:44Z-
dc.date.issued2019-
dc.identifier.issn0251-5350-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/170968-
dc.description.abstractBACKGROUND: Restless legs syndrome (RLS) is a common sleep disorder, although it has a low prevalence in Asian populations. However, the reported RLS prevalence in -Korean adults is mostly 4.5-12.1%, which is higher than that reported in other Asian populations. This study aimed to diagnose RLS and exclude mimicking conditions in 2 independent samples of Korean adults, and to compare its prevalence to that from previous studies performed in Asian countries. METHODS: Study populations included a (1) nationwide stratified random sample (n = 2,824; age 19-79 years) and (2) community-based cohort (n = 2,685; age 47-79 years). We applied the Cambridge-Hopkins diagnostic questionnaire to diagnose RLS and differentiate it from RLS mimics. Sleep-related symptoms, mood, and medical conditions were compared between the RLS and non-RLS groups. Prior studies of the RLS prevalence in Asia were systematically reviewed and compared to our findings. RESULTS: The adjusted RLS prevalence was 0.4 and 1.3% in populations 1 and 2, respectively. In both populations, subjects with RLS had more depression. The prevalence of RLS mimics was 5.1 and 2.6%, in populations 1 and 2, respectively. The RLS prevalence in Asia was higher when RLS was defined by the presence of essential clinical features and lower when a differential diagnosis was additionally implemented. CONCLUSIONS: The RLS prevalence in Korean adults considering RLS mimics is comparable to that in adults from other Asian countries (< 2%). The reported RLS prevalence varies depending on the diagnostic method employed.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherS. Karger-
dc.relation.isPartOfNeuroepidemiology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titlePrevalence and Characteristics of Restless Legs Syndrome in Korean Adults: A Study in Two Independent Samples of the General Population-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.googleauthorKim T.-J.-
dc.contributor.googleauthorYoon J.E.-
dc.contributor.googleauthorPark J.A-
dc.contributor.googleauthorLee S.K.-
dc.contributor.googleauthorChu M.K.-
dc.contributor.googleauthorYang K.I.-
dc.contributor.googleauthorKim W.-J.-
dc.contributor.googleauthorPark S.-H.-
dc.contributor.googleauthorThomas R.J.-
dc.contributor.googleauthorShin C.-
dc.contributor.googleauthorYun C.-H-
dc.identifier.doi10.1159/000496839-
dc.contributor.localIdA03950-
dc.relation.journalcodeJ02328-
dc.identifier.eissn1423-0208-
dc.identifier.pmid30763945-
dc.identifier.urlhttps://www.karger.com/Article/Abstract/496839-
dc.subject.keywordCambridge-Hopkins diagnostic questionnaire-
dc.subject.keywordEpidemiology-
dc.subject.keywordRestless legs syndrome-
dc.contributor.alternativeNameChu, Min Kyung-
dc.contributor.affiliatedAuthor주민경-
dc.citation.volume52-
dc.citation.number3~4-
dc.citation.startPage193-
dc.citation.endPage204-
dc.identifier.bibliographicCitationNeuroepidemiology, Vol.52(3~4) : 193-204, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

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