Cited 14 times in
Effects of ultraviolet treatment and alendronate immersion on osteoblast-like cells and human gingival fibroblasts cultured on titanium surfaces
DC Field | Value | Language |
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dc.contributor.author | 문홍석 | - |
dc.contributor.author | 오경철 | - |
dc.contributor.author | 전창주 | - |
dc.date.accessioned | 2019-09-20T07:34:35Z | - |
dc.date.available | 2019-09-20T07:34:35Z | - |
dc.date.issued | 2019 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/170957 | - |
dc.description.abstract | In this study, we evaluated the effects of ultraviolet (UV) treatment and alendronate (ALN) immersion on the proliferation and differentiation of MG-63 osteoblast-like cells and human gingival fibroblasts (HGFs) cultured on titanium surfaces. MG-63 cells were used for sandblasted, large grit, and acid-etched (SLA) titanium surfaces, and HGFs were used for machined (MA) titanium surfaces. SLA and MA specimens were subdivided into four groups (n = 12) according to the combination of surface treatments (UV treatment and/or ALN immersion) applied. After culturing MG-63 cells and HGFs on titanium discs, cellular morphology, proliferation, and differentiation were evaluated. The results revealed that UV treatment of titanium surfaces did not alter the proliferation of MG-63 cells; however, HGF differentiation and adhesion were increased in response to UV treatment. In contrast, ALN immersion of titanium discs reduced MG-63 cell proliferation and changed HGFs into a more atrophic form. Simultaneous application of UV treatment and ALN immersion induced greater differentiation of MG-63 cells. Within the limitations of this cellular level study, simultaneous application of UV treatment and ALN immersion of titanium surfaces was shown to improve the osseointegration of titanium implants; in addition, UV treatment may be used to enhance mucosal sealing of titanium abutments. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | Scientific Reports | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Effects of ultraviolet treatment and alendronate immersion on osteoblast-like cells and human gingival fibroblasts cultured on titanium surfaces | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Prosthodontics (보철과학교실) | - |
dc.contributor.googleauthor | Changjoo Jeon | - |
dc.contributor.googleauthor | Kyung Chul Oh | - |
dc.contributor.googleauthor | Kyu-Hyung Park | - |
dc.contributor.googleauthor | Hong Seok Moon | - |
dc.identifier.doi | 10.1038/s41598-019-39355-3 | - |
dc.contributor.localId | A01395 | - |
dc.contributor.localId | A04976 | - |
dc.contributor.localId | A05658 | - |
dc.relation.journalcode | J02646 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.pmid | 30796313 | - |
dc.contributor.alternativeName | Moon, Hong Seok | - |
dc.contributor.affiliatedAuthor | 문홍석 | - |
dc.contributor.affiliatedAuthor | 오경철 | - |
dc.contributor.affiliatedAuthor | 전창주 | - |
dc.citation.volume | 9 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 2581 | - |
dc.identifier.bibliographicCitation | Scientific Reports, Vol.9(1) : 2581, 2019 | - |
dc.identifier.rimsid | 64296 | - |
dc.type.rims | ART | - |
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