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Demographic and clinical features of hidradenitis suppurativa in Korea

 Ji Hoon YANG  ;  Jungyoon MOON  ;  Young Chul KYE  ;  Kwang Joong KIM  ;  Myeung Nam KIM  ;  Young Suck RO  ;  Mi Youn PARK  ;  Hyo Hyun AHN  ;  Mi Woo LEE  ;  Weon Ju LEE  ;  Ju Hee LEE  ;  Jee Bum LEE  ;  Min Soo JANG  ;  Yu Sung CHOI  ;  You Won CHOI  ;  Dae Hun SUH 
 Dermatology, Vol.45(12) : 1389-1395, 2018 
Journal Title
Issue Date
Acne Vulgaris/epidemiology* ; Adolescent ; Adult ; Body Mass Index ; Child ; Child, Preschool ; Comorbidity ; Diabetes Mellitus/epidemiology* ; Female ; Hidradenitis Suppurativa/diagnosis ; Hidradenitis Suppurativa/epidemiology* ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Prevalence ; Republic of Korea/epidemiology ; Retrospective Studies ; Risk Factors ; Severity of Illness Index ; Sex Factors ; Smoking/epidemiology* ; Young Adult
Asia ; epidemiology ; hidradenitis suppurativa ; severity ; treatment
Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disorder. Although several epidemiological studies have been conducted in Western countries, such data regarding Asian populations are scarce. In this study, we sought to investigate the demographic and clinical features of HS in Korea. A total of 438 patients, diagnosed with HS from May 2007 to April 2017, were enrolled and the electronic medical record of each patient was reviewed. Male patients were predominant with a male : female ratio of 2.5:1. Mean age of disease onset was 23.9 years and most patients had no family history. The most frequently affected area was the buttocks, followed by axillae and groin. Acne and diabetes mellitus were the most prevalent associated diseases and no patients with inflammatory bowel diseases were observed. In the univariable analysis, male patients had severe diseases compared with females with an odds ratio (OR) of 1.790. Two or more affected body regions were associated with HS severity with an OR of 1.693. While involvement of the perineum (OR, 4.067) and buttocks (OR, 1.471) tended to be associated with increased severity of the disease, the inguinal area (OR, 0.620) showed a tendency to be inversely associated with the severity. In multivariable analysis, identified risk factors were the involvement of the perineum (OR, 3.819) and buttocks (OR, 2.288). Smoking status and high body mass index seemed to be associated with more severe diseases. Our results will provide clinical characteristics of HS patients in Asia and help to broaden understanding of HS.
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1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Ju Hee(이주희) ORCID logo https://orcid.org/0000-0002-1739-5956
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