Cited 45 times in
Interobserver and intraobserver variation in the morphological evaluation of noninvasive follicular thyroid neoplasm with papillary-like nuclear features in Asian practice
DC Field | Value | Language |
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dc.contributor.author | 홍순원 | - |
dc.date.accessioned | 2019-07-23T06:50:59Z | - |
dc.date.available | 2019-07-23T06:50:59Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1320-5463 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/170335 | - |
dc.description.abstract | To evaluate the current diagnostic criteria in reportingnuclearfeaturesofnoninvasivefollicularthyroidneoplasmwithpapillary-likenuclearfeatures(NIFTP), nineAsianpathologists with expertise inthyroidreviewed virtual slides of 30noninvasivefollicularpatternedthyroidlesions according to thenuclearscoring system originally proposed by an international expert and a more detailed scoring system proposed by theAsianWorking Group. Theinterobserveragreement fornucleargrading score was generally moderate (kappa value = 0.452). The best consistency fell on the chromatinfeatures(kappa value = 0.658-1.000). A fair to moderateinterobserveragreement was demonstrated in theevaluationofnuclearelongation,nuclearoverlapping, membrane irregularities and distribution of papillarythyroidcarcinoma (PTC) typenuclearfeatures. A slight agreement was rendered for theevaluationof thenuclearenlargement.Intraobserveragreement was substantial to perfect when comparing results of both scoring systems. However, both scoring systems were not able to reliably separate NIFTP from an encapsulatedfollicularvariant PTC with minimal lymph node metastasis or BRAFV600Emutation. Although the three-pointnuclearscoring system for the diagnosis of NIFTP is widely used inAsianpractice,interobservervariationwas considerable. Ancillary immunohistochemical or molecular testing might be helpful in differentiating NIFTP from true PTC. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Blackwell Scientific Publications for the Japanese Society of Pathology | - |
dc.relation.isPartOf | PATHOLOGY INTERNATIONAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma,Follicular/diagnosis | - |
dc.subject.MESH | Adenocarcinoma,Follicular/genetics | - |
dc.subject.MESH | Adenocarcinoma,Follicular/pathology | - |
dc.subject.MESH | Amino Acid Substitution | - |
dc.subject.MESH | AsianContinental Ancestry Group | - |
dc.subject.MESH | Biopsy, Fine-Needle | - |
dc.subject.MESH | Cell Nucleus/pathology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lymphatic Metastasis | - |
dc.subject.MESH | Mutation | - |
dc.subject.MESH | ObserverVariation | - |
dc.subject.MESH | Proto-Oncogene Proteins B-raf/genetics | - |
dc.subject.MESH | ThyroidCancer, Papillary/diagnosis | - |
dc.subject.MESH | ThyroidCancer, Papillary/genetics | - |
dc.subject.MESH | ThyroidCancer, Papillary/pathology | - |
dc.subject.MESH | ThyroidGland/pathology | - |
dc.subject.MESH | ThyroidNeoplasms/diagnosis | - |
dc.subject.MESH | ThyroidNeoplasms/genetics | - |
dc.subject.MESH | ThyroidNeoplasms/pathology | - |
dc.title | Interobserver and intraobserver variation in the morphological evaluation of noninvasive follicular thyroid neoplasm with papillary-like nuclear features in Asian practice | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학교실) | - |
dc.contributor.googleauthor | Zhiyan Liu | - |
dc.contributor.googleauthor | Andrey Bychkov | - |
dc.contributor.googleauthor | Chan Kwon Jung | - |
dc.contributor.googleauthor | Mitsuyoshi Hirokawa | - |
dc.contributor.googleauthor | Shaofeng Sui | - |
dc.contributor.googleauthor | SoonWon Hong | - |
dc.contributor.googleauthor | Chiung‐Ru Lai | - |
dc.contributor.googleauthor | Deepali Jain | - |
dc.contributor.googleauthor | Sule Canberk | - |
dc.contributor.googleauthor | Kennichi Kakudo | - |
dc.identifier.doi | 10.1111/pin.12779 | - |
dc.contributor.localId | A04411 | - |
dc.relation.journalcode | J02473 | - |
dc.identifier.eissn | 1440-1827 | - |
dc.identifier.pmid | 30811774 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/full/10.1111/pin.12779 | - |
dc.subject.keyword | digital pathology | - |
dc.subject.keyword | noninvasivefollicularthyroidneoplasmwithpapillary-likenuclearfeatures | - |
dc.subject.keyword | nuclearscoring system | - |
dc.subject.keyword | observervariation | - |
dc.subject.keyword | tumors of uncertain malignant potential | - |
dc.contributor.alternativeName | Hong, Soon Won | - |
dc.contributor.affiliatedAuthor | 홍순원 | - |
dc.citation.volume | 69 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 202 | - |
dc.citation.endPage | 210 | - |
dc.identifier.bibliographicCitation | PATHOLOGY INTERNATIONAL, Vol.69(4) : 202-210, 2019 | - |
dc.identifier.rimsid | 62289 | - |
dc.type.rims | ART | - |
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