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Comparing Properties of Variable Pore-Sized 3D-Printed PLA Membrane with Conventional PLA Membrane for Guided Bone/Tissue Regeneration

DC Field Value Language
dc.contributor.author강효진-
dc.contributor.author권재성-
dc.contributor.author김광만-
dc.date.accessioned2019-07-23T06:50:36Z-
dc.date.available2019-07-23T06:50:36Z-
dc.date.issued2019-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/170330-
dc.description.abstractThe aim of this study was to fabricate bioresorbable polylactide (PLA) membranes by 3D printing and compare theirpropertiesto those of the membranes fabricated by theconventionalmethod and compare the effect of different pore sizes on thepropertiesof the3D-printedmembranes.PLAmembranes with three different pore sizes (large pore-479 μm, small pore-273 μm, and no pore) were3D printed, and membranes fabricated using theconventionalsolvent casting method were used as the control group. Scanning electron microscopy (SEM) and micro-computed tomography (µ-CT) were taken to observe the morphology and obtain the porosity of the four groups. A tensile test was performed to compare the tensile strength, elastic modulus, and elongation at break of the membranes. Preosteoblast cells were cultured on the membranes for 1, 3 and 7 days, followed by a WST assay and SEM, to examine the cell proliferation on different groups. As a result, the3D-printedmembranes showed superior mechanicalpropertiesto those of the solvent cast membranes, and the3D-printedmembranes exhibited different advantageous mechanicalpropertiesdepending on the different pore sizes. The various fabrication methods and pore sizes did not have significantly different effects on cell growth. It is proven that 3D printing is a promising method for the fabrication of customized barrier membranes used in GBR/GTR.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI-
dc.relation.isPartOfMATERIALS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESH3D printing-
dc.subject.MESHartificial membranes-
dc.subject.MESHbiomaterials-
dc.subject.MESHguided bone regeneration-
dc.subject.MESHguided tissueregeneration-
dc.subject.MESHpolylactide-
dc.titleComparing Properties of Variable Pore-Sized 3D-Printed PLA Membrane with Conventional PLA Membrane for Guided Bone/Tissue Regeneration-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentBioMedical Science Institute (의생명과학부)-
dc.contributor.googleauthorHao Yang Zhang-
dc.contributor.googleauthorHeng Bo Jiang-
dc.contributor.googleauthorJeong-Hyun Ryu-
dc.contributor.googleauthorHyojin Kang-
dc.contributor.googleauthorKwang-Mahn Kim-
dc.contributor.googleauthorJae-Sung Kwon-
dc.identifier.doi10.3390/ma12101718-
dc.contributor.localIdA00101-
dc.contributor.localIdA00247-
dc.contributor.localIdA00247-
dc.contributor.localIdA00312-
dc.contributor.localIdA00312-
dc.relation.journalcodeJ02182-
dc.identifier.eissn1996-1944-
dc.identifier.pmid31137830-
dc.contributor.alternativeNameKang, Hyo Jin-
dc.contributor.affiliatedAuthor강효진-
dc.contributor.affiliatedAuthor권재성-
dc.contributor.affiliatedAuthor권재성-
dc.contributor.affiliatedAuthor김광만-
dc.contributor.affiliatedAuthor김광만-
dc.citation.volume12-
dc.citation.number10-
dc.citation.startPageE1718-
dc.identifier.bibliographicCitationMATERIALS, Vol.12(10) : E1718, 2019-
dc.identifier.rimsid62007-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers

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