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Psychotic conversion of individuals at ultra-high risk for psychosis: The potential roles of schizotypy and basic symptoms
DC Field | Value | Language |
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dc.contributor.author | 강지인 | - |
dc.contributor.author | 김경란 | - |
dc.contributor.author | 박진영 | - |
dc.contributor.author | 안석균 | - |
dc.contributor.author | 이은 | - |
dc.date.accessioned | 2019-07-23T06:45:04Z | - |
dc.date.available | 2019-07-23T06:45:04Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1751-7885 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/170293 | - |
dc.description.abstract | AIM: To improve strategies for the early identification of individuals at a heightened risk for the development of psychosis, we investigated the relationships and interactions between 3 psychosis-proneness dimensions for the development of schizophrenia spectrum psychosis: schizotypy, basic symptoms and the ultra-high risk (UHR) criteria. METHODS: Seventy-seven UHR individuals and 79 healthy controls were assessed for schizotypy and basic symptoms using self-report questionnaires at baseline. UHR participants were monthly assessed for conversion to psychosis over a mean period of 25.8 months. RESULTS: Sixteen UHR participants (20.8%) converted to schizophrenia spectrum psychosis. In stepwise Cox regression, the interaction between basic symptoms and physical anhedonia was selected as a sole predictor of conversion in UHR participants, whereby the self-reported number of the 8 basic symptoms significantly increased the risk for conversion in those with pronounced physical anhedonia. CONCLUSION: Our findings suggest that questionnaire-assessed basic symptoms, irrespective of their predictive validity, may predict a psychotic breakdown in pre-identified UHR individuals who are with genetic vulnerability to schizophrenia. Including all 3 psychosis-proneness dimensions into prediction models might help establish a more valid pathogenetic model of schizophrenia, and moreover, may provide some clues about course alteration strategies in hopes of preventing UHR individuals from converting to psychosis. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley-Blackwell | - |
dc.relation.isPartOf | EARLY INTERVENTION IN PSYCHIATRY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Psychotic conversion of individuals at ultra-high risk for psychosis: The potential roles of schizotypy and basic symptoms | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Psychiatry (정신과학교실) | - |
dc.contributor.googleauthor | Minji Bang | - |
dc.contributor.googleauthor | Jin Young Park | - |
dc.contributor.googleauthor | Kyung Ran Kim | - |
dc.contributor.googleauthor | Su Young Lee | - |
dc.contributor.googleauthor | Yun Young Song | - |
dc.contributor.googleauthor | Jee In Kang | - |
dc.contributor.googleauthor | Eun Lee | - |
dc.contributor.googleauthor | Suk Kyoon An | - |
dc.identifier.doi | 10.1111/eip.12518 | - |
dc.contributor.localId | A00084 | - |
dc.contributor.localId | A00293 | - |
dc.contributor.localId | A01701 | - |
dc.contributor.localId | A02227 | - |
dc.contributor.localId | A03032 | - |
dc.relation.journalcode | J00755 | - |
dc.identifier.eissn | 1751-7893 | - |
dc.identifier.pmid | 29218852 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/full/10.1111/eip.12518 | - |
dc.subject.keyword | basicsymptoms | - |
dc.subject.keyword | physical anhedonia | - |
dc.subject.keyword | schizophrenia | - |
dc.subject.keyword | schizotypy | - |
dc.subject.keyword | ultra-highriskforpsychosis | - |
dc.contributor.alternativeName | Kang, Jee In | - |
dc.contributor.affiliatedAuthor | 강지인 | - |
dc.contributor.affiliatedAuthor | 김경란 | - |
dc.contributor.affiliatedAuthor | 박진영 | - |
dc.contributor.affiliatedAuthor | 안석균 | - |
dc.contributor.affiliatedAuthor | 이은 | - |
dc.citation.volume | 13 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 546 | - |
dc.citation.endPage | 554 | - |
dc.identifier.bibliographicCitation | EARLY INTERVENTION IN PSYCHIATRY, Vol.13(3) : 546-554, 2019 | - |
dc.identifier.rimsid | 61911 | - |
dc.type.rims | ART | - |
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