Effectsofdifferenttypesandfrequenciesofphysical activityon thehomeostaticmodelassessmentofinsulin resistance

Abstract

This study analyzed the type andfrequencyofphysical activitythat mosteffectivelyreduces thehomeostaticmodelassessmentofinsulin resistance(HOMA2-IR) among adults (≥19 years) in Asia. We used national representative data from 1645 men and 2272 women who participated in the Korea National Health and Nutrition Examination Survey in 2015 were included in the analysis. Theeffectsofdifferenttypesandfrequenciesofphysical activityon HOMA2-IR were investigated using a multiple regression analysis. Compared with noactivity, moderate-to-vigorousphysical activity(MVPA) ≥5 times per week (β: -0.214, p≤0.0198) and walking and MVPA ≥5 times per week (β: -0.183, p≤0.0049) were negatively associated with HOMA2-IR. In the subgroup analysis, the strongesteffectwas observed among overweight men. Additionally, walking plus MVPA ≥5 times per week had the strongesteffecton men with a higher-than-recommended daily calorie intake (β: -0.350, p≤0.0030). Therefore, in conclusion, the appropriate type andfrequencyofphysical activitycan help reduce HOMA2-IR in South Korean men, especially those who are overweight and/or have a higher-than-recommended daily calorie intake.