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Histological features of intracranial thrombi in stroke patients with cancer

Authors
 Hyungjong Park  ;  Jayoung Kim  ;  Jimin Ha  ;  In Gun Hwang  ;  Tae-Jin Song  ;  Joonsang Yoo  ;  Seong Hwan Ahn  ;  Kyoungsub Kim  ;  Byung Moon Kim  ;  Dong Joon Kim  ;  Young Dae Kim  ;  Hyo Suk Nam  ;  Il Kwon  ;  Hyun-Jung Choi  ;  Sung-il Sohn  ;  Hye Sun Lee  ;  Ji Hoe Heo 
Citation
 ANNALS OF NEUROLOGY, Vol.86(1) : 143-149, 2019 
Journal Title
 ANNALS OF NEUROLOGY 
ISSN
 0364-5134 
Issue Date
2019
Abstract
The histological features of thrombus in stroke patients with cancer are not well known. Using immunohistochemical staining of thrombiretrieved during mechanical thrombectomy in stroke patients, thrombus compositions were compared between 16 patients with active cancer, 16 patients with inactive cancer, and 16 patients without any history of cancer. The active cancer group showed higher platelet and lower erythrocyte fractions than the inactive cancer or the control group. Four patients with vegetation showed very high platelet and low erythrocyte fractions. Patients with cryptogenic etiology in the active cancer group showed a similar pattern to those with vegetation. These findings may aid the determination of treatment strategies in cancer-associated stroke.
Full Text
https://onlinelibrary.wiley.com/doi/full/10.1002/ana.25495
DOI
10.1002/ana.25495
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
Yonsei Authors
Kim, Kyoung Sub(김경섭)
Kim, Dong Joon(김동준) ORCID logo https://orcid.org/0000-0002-7035-087X
Kim, Byung Moon(김병문) ORCID logo https://orcid.org/0000-0001-8593-6841
Kim, Young Dae(김영대) ORCID logo https://orcid.org/0000-0001-5750-2616
Nam, Hyo Suk(남효석) ORCID logo https://orcid.org/0000-0002-4415-3995
Park, Hyungjong(박형종)
Lee, Hye Sun(이혜선) ORCID logo https://orcid.org/0000-0001-6328-6948
Heo, Ji Hoe(허지회) ORCID logo https://orcid.org/0000-0001-9898-3321
Hwang, In Gun(황인건) ORCID logo https://orcid.org/0000-0002-5193-4060
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/170239
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