Cited 34 times in
Comparison of Characteristics and 3-Year Outcomes in Patients With Acute Heart Failure With Preserved, Mid-Range, and Reduced Ejection Fraction
DC Field | Value | Language |
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dc.contributor.author | 강석민 | - |
dc.date.accessioned | 2019-07-11T03:32:00Z | - |
dc.date.available | 2019-07-11T03:32:00Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/170019 | - |
dc.description.abstract | BACKGROUND: The clinical characteristics and outcomes of acute heart failure (AHF) according to left ventricular ejection fraction (LVEF) have not been fully elucidated, especially for patients with mid-range LVEF. We performed a comprehensive comparison of the epidemiology, patterns of in-hospital management, and clinical outcomes in AHF patients with different LVEF categories. Methods and Results: The Korean Acute Heart Failure (KorAHF) registry is a prospective multicenter cohort of hospitalized AHF patients in Korea. A total of 5,374 patients enrolled in the KorAHF registry were classified according to LVEF based on the 2016 ESC guidelines. More than half of the HF patients (58%) had reduced EF (HFrEF), 16% had mid-range EF (HFmrEF), and 25% had preserved EF (HFpEF). The HFmrEF patients showed intermediate epidemiological profiles between HFrEF and HFpEF and had a propensity to present as de-novo HF with ischemic etiology. Patients with lower LVEF had worse short-term outcomes, and the all-cause in-hospital mortality, including urgent heart transplantation, of HFrEF, HFmrEF, and HFpEF was 7.1%, 3.6%, and 3.0%, respectively. Overall, discharged AHF patients showed poor 3-year all-cause death up to 38%, which was comparable between LVEF subgroups (P=0.623). CONCLUSIONS: Each LVEF subgroup of AHF patients was a heterogeneous population with diverse characteristics, which have a significant effect on the clinical outcomes. This finding suggested that focused phenotyping of AHF patients could help identify the optimal management strategy and develop novel effective therapies. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English, Japanese | - |
dc.publisher | Japanese Circulation Society | - |
dc.relation.isPartOf | CIRCULATION JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Comparison of Characteristics and 3-Year Outcomes in Patients With Acute Heart Failure With Preserved, Mid-Range, and Reduced Ejection Fraction | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jun Hwan Cho | - |
dc.contributor.googleauthor | Won-Seok Choe | - |
dc.contributor.googleauthor | Hyun-Jai Cho | - |
dc.contributor.googleauthor | Hae-Young Lee | - |
dc.contributor.googleauthor | Jieun Jang | - |
dc.contributor.googleauthor | Sang Eun Lee | - |
dc.contributor.googleauthor | Jin-Oh Choi | - |
dc.contributor.googleauthor | Eun-Seok Jeon | - |
dc.contributor.googleauthor | Min-Seok Kim | - |
dc.contributor.googleauthor | Kyung-Kuk Hwang | - |
dc.contributor.googleauthor | Shung Chull Chae | - |
dc.contributor.googleauthor | Sang Hong Baek | - |
dc.contributor.googleauthor | Seok-Min Kang | - |
dc.contributor.googleauthor | Dong-Ju Choi | - |
dc.contributor.googleauthor | Byung-Su Yoo | - |
dc.contributor.googleauthor | Kye Hun Kim | - |
dc.contributor.googleauthor | Myeong-Chan Cho | - |
dc.contributor.googleauthor | Jae-Joong Kim | - |
dc.contributor.googleauthor | Byung-Hee Oh | - |
dc.identifier.doi | 10.1253/circj.CJ-18-0543 | - |
dc.contributor.localId | A00037 | - |
dc.relation.journalcode | J00534 | - |
dc.identifier.eissn | 1347-4820 | - |
dc.identifier.pmid | 30404976 | - |
dc.subject.keyword | Acute heart failure | - |
dc.subject.keyword | Left ventricular ejection fraction | - |
dc.subject.keyword | Outcomes | - |
dc.subject.keyword | Survival | - |
dc.contributor.alternativeName | Kang, Seok Min | - |
dc.contributor.affiliatedAuthor | 강석민 | - |
dc.citation.volume | 83 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 347 | - |
dc.citation.endPage | 356 | - |
dc.identifier.bibliographicCitation | CIRCULATION JOURNAL, Vol.83(2) : 347-356, 2019 | - |
dc.identifier.rimsid | 62748 | - |
dc.type.rims | ART | - |
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