39 52

Cited 2 times in

Lessons Learned From GWAS of Asthma

DC FieldValueLanguage
dc.contributor.author김경원-
dc.date.accessioned2019-07-11T03:17:46Z-
dc.date.available2019-07-11T03:17:46Z-
dc.date.issued2019-
dc.identifier.issn2092-7355-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/169913-
dc.description.abstractAsthma is a common complex disease of the airways. Genome-wide association studies (GWASs) of asthma have identified many risk alleles and loci that have been replicated in worldwide populations. Although the risk alleles identified by GWAS have small effects and explain only a small portion of prevalence, the discovery of asthma loci can provide an understanding of its genetic architecture and the molecular pathways involved in disease pathogenesis. These discoveries can translate into advances in clinical care by identifying therapeutic targets, preventive strategies and ultimately approaches for personalized medicine. In this review, we summarize results from GWAS of asthma from the past 10 years and the insights gleaned from these discoveries.-
dc.description.statementOfResponsibilityopen-
dc.publisherKorean Academy of Pediatric Allergy and Respiratory Disease-
dc.relation.isPartOfALLERGY ASTHMA & IMMUNOLOGY RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleLessons Learned From GWAS of Asthma-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아청소년과학교실)-
dc.contributor.googleauthorKyung Won Kim-
dc.contributor.googleauthorCarole Ober-
dc.identifier.doi10.4168/aair.2019.11.2.170-
dc.contributor.localIdA00303-
dc.relation.journalcodeJ00064-
dc.identifier.eissn2092-7363-
dc.identifier.pmid30661310-
dc.subject.keywordAsthma-
dc.subject.keywordgenome-wide association study-
dc.contributor.alternativeNameKim, Kyung Won-
dc.contributor.affiliatedAuthor김경원-
dc.citation.volume11-
dc.citation.number2-
dc.citation.startPage170-
dc.citation.endPage187-
dc.identifier.bibliographicCitationALLERGY ASTHMA & IMMUNOLOGY RESEARCH, Vol.11(2) : 170-187, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.