Cited 13 times in
Exercise and incidence of myocardial infarction, stroke, hypertension, type 2 diabetes and site-specific cancers: prospective cohort study of 257 854 adults in South Korea
DC Field | Value | Language |
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dc.contributor.author | 지선하 | - |
dc.date.accessioned | 2019-07-11T03:17:15Z | - |
dc.date.available | 2019-07-11T03:17:15Z | - |
dc.date.issued | 2019 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/169907 | - |
dc.description.abstract | OBJECTIVE: The objective of this study was to examine the longitudinal associations of exercise frequency with the incidence of myocardial infarction, stroke, hypertension, type 2 diabetes and 10 different cancer outcomes. DESIGN: A prospective cohort study. SETTING: Physical examination data linked with the entire South Korean population's health insurance system: from 2002 to 2015. PARTICIPANTS: 257 854 South Korean adults who provided up to 7 repeat measures of exercise (defined as exercises causing sweat) and confounders. PRIMARY OUTCOME MEASURES: Each disease incidence was defined using both fatal and non-fatal health records (a median follow-up period of 13 years). RESULTS: Compared with no exercise category, the middle categories of exercise frequency (3-4 or 5-6 times/week) showed the lowest risk of myocardial infarction (HR 0.79; 95% CI 0.70 to 0.90), stroke (HR 0.80; 95% CI 0.73 to 0.89), hypertension (HR 0.86; 95% CI 0.85 to 0.88), type 2 diabetes (HR 0.87; 95% CI 0.84 to 0.89), stomach (HR 0.87; 95% CI 0.79 to 0.96), lung (HR 0.80; 95% CI 0.71 to 0.91), liver (HR 0.85; 95% CI 0.75 to 0.98) and head and neck cancers (HR 0.76; 95% CI 0.63 to 0.93; for 1-2 times/week), exhibiting J-shaped associations. There was, in general, little evidence of effect modification by body mass index, smoking, alcohol consumption, family history of disease and sex in these associations. CONCLUSIONS: Moderate levels of sweat-inducing exercise showed the lowest risk of myocardial infarction, stroke, hypertension, type 2 diabetes, stomach, lung, liver and head and neck cancers. Public health and lifestyle interventions should, therefore, promote moderate levels of sweat-causing exercise as a behavioural prevention strategy for non-communicable diseases in a wider population of East Asians. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | BMJ Publishing Group Ltd | - |
dc.relation.isPartOf | BMJ OPEN | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Exercise and incidence of myocardial infarction, stroke, hypertension, type 2 diabetes and site-specific cancers: prospective cohort study of 257 854 adults in South Korea | - |
dc.type | Article | - |
dc.contributor.college | Graduate School of Public Health (보건대학원) | - |
dc.contributor.department | Graduate School of Public Health (보건대학원) | - |
dc.contributor.googleauthor | Youngwon Kim | - |
dc.contributor.googleauthor | Stephen Sharp | - |
dc.contributor.googleauthor | Semi Hwang | - |
dc.contributor.googleauthor | Sun Ha Jee | - |
dc.identifier.doi | 10.1136/bmjopen-2018-025590 | - |
dc.contributor.localId | A03965 | - |
dc.relation.journalcode | J00380 | - |
dc.identifier.eissn | 2044-6055 | - |
dc.identifier.pmid | 30872551 | - |
dc.subject.keyword | cardiovascular disease | - |
dc.subject.keyword | cohort | - |
dc.subject.keyword | epidemiology | - |
dc.subject.keyword | exercise | - |
dc.subject.keyword | hypertension | - |
dc.subject.keyword | non-communicable disease | - |
dc.contributor.alternativeName | Jee, Sun Ha | - |
dc.contributor.affiliatedAuthor | 지선하 | - |
dc.citation.volume | 9 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | e025590 | - |
dc.identifier.bibliographicCitation | BMJ OPEN, Vol.9(3) : e025590, 2019 | - |
dc.identifier.rimsid | 61881 | - |
dc.type.rims | ART | - |
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