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The lung allocation score could evaluate allocation systems in countries that do not use the score

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dc.contributor.author김송이-
dc.contributor.author박무석-
dc.contributor.author백효채-
dc.contributor.author서지원-
dc.contributor.author송승환-
dc.contributor.author이진구-
dc.date.accessioned2019-07-11T03:15:32Z-
dc.date.available2019-07-11T03:15:32Z-
dc.date.issued2019-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/169890-
dc.description.abstractBACKGROUND: Evaluating allocation system effects on lung transplantation and determining systemic flaws is difficult. The purpose of this study was to assess the Korean urgency-based lung allocation system using the lung allocation score. METHODS: We reviewed transplantation patients retrospectively. Candidates were classified into groups based on urgency. Status 0 designated hospitalized patients requiring ventilator and/or extracorporeal life support. The lung allocation score was calculated based on the recipient's condition at transplantation. RESULTS: One-hundred-twenty-three Status 0, 1, and 2/3 patients (40, 71, and 12, respectively) were enrolled. The median waiting time was 68 days. Nineteen Status 0 patients who received lung transplants deteriorated from non-Status 0 (median, 64 days). The lung allocation score showed a bimodal distribution (peaks around 45 and 90, corresponding with non-Status 0 and Status 0, respectively). Status 0 and the lung allocation score were independent risk factors for poor survival after adjustment for confounders (Status 0, hazard ratio, 2.788, p = 0.001; lung allocation score, hazard ratio, 1.025, p < 0.001). The lung allocation score cut-off for survival was 44. On dividing the non-Status 0 patients into 2 groups using the cut-off values and regrouping into Status 0, non-Status 0 with high lung allocation score (> 44), and non-Status 0 with low lung allocation score (< 44), we observed that non-Status 0 with high lung allocation score patients had better survival than Status 0 patients (p = 0.020) and poorer survival than non-Status 0 with low lung allocation score patients (p = 0.018). CONCLUSIONS: The LAS demonstrated the characteristics of LTx recipients in Korea and the Korean allocation system needs to be revised to reduce the number of patients receiving LTx in Status 0. The LAS system could be used as a tool to evaluate lung allocation systems in countries that do not use the LAS system.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherPublic Library of Science-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleThe lung allocation score could evaluate allocation systems in countries that do not use the score-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorWoo Sik Yu-
dc.contributor.googleauthorJee Won Suh-
dc.contributor.googleauthorSeung Hwan Song-
dc.contributor.googleauthorHyo Chae Paik-
dc.contributor.googleauthorSong Yee Kim-
dc.contributor.googleauthorMoo Suk Park-
dc.contributor.googleauthorJin Gu Lee-
dc.identifier.doi10.1371/journal.pone.0214853-
dc.contributor.localIdA00626-
dc.contributor.localIdA01457-
dc.contributor.localIdA01457-
dc.contributor.localIdA01846-
dc.contributor.localIdA01846-
dc.contributor.localIdA04956-
dc.contributor.localIdA04956-
dc.contributor.localIdA04963-
dc.contributor.localIdA04963-
dc.contributor.localIdA03225-
dc.contributor.localIdA03225-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid30943262-
dc.contributor.alternativeNameKim, Song Yee-
dc.contributor.affiliatedAuthor김송이-
dc.contributor.affiliatedAuthor박무석-
dc.contributor.affiliatedAuthor박무석-
dc.contributor.affiliatedAuthor백효채-
dc.contributor.affiliatedAuthor백효채-
dc.contributor.affiliatedAuthor서지원-
dc.contributor.affiliatedAuthor서지원-
dc.contributor.affiliatedAuthor송승환-
dc.contributor.affiliatedAuthor송승환-
dc.contributor.affiliatedAuthor이진구-
dc.contributor.affiliatedAuthor이진구-
dc.citation.volume14-
dc.citation.number4-
dc.citation.startPagee0214853-
dc.identifier.bibliographicCitationPLOS ONE, Vol.14(4) : e0214853, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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