Cited 45 times in
Urinary Potassium Excretion and Progression of CKD
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강신욱 | - |
dc.contributor.author | 김형우 | - |
dc.contributor.author | 박정탁 | - |
dc.contributor.author | 유태현 | - |
dc.contributor.author | 최규헌 | - |
dc.contributor.author | 한승혁 | - |
dc.date.accessioned | 2019-05-29T05:07:28Z | - |
dc.date.available | 2019-05-29T05:07:28Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1555-9041 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/169414 | - |
dc.description.abstract | BACKGROUND AND OBJECTIVES: Data on whether low or high urinary potassium excretion is associated with poor kidney outcome have been conflicting. The aim of this study was to clarify the association between urinary potassium excretion and CKD progression. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We investigated the relationship between lower urinary potassium excretion and CKD progression and compared three urinary potassium indices among 1821 patients from the Korean Cohort Study for Outcome in Patients with CKD. Urinary potassium excretion was determined using spot urinary potassium-to-creatinine ratio, spot urinary potassium concentration, and 24-hour urinary potassium excretion. Patients were categorized into four groups according to quartiles of each urinary potassium excretion metric. The study end point was a composite of a ≥50% decrease in eGFR from baseline values and ESKD. RESULTS: During 5326 person-years of follow-up, the primary outcome occurred in 392 (22%) patients. In a multivariable cause-specific hazard model, lower urinary potassium-to-creatinine ratio was associated with higher risk of CKD progression (adjusted hazard ratio, 1.47; 95% confidence interval, 1.01 to 2.12) comparing the lowest quartile with the highest quartile. Sensitivity analyses with other potassium metrics also showed consistent results in 855 patients who completed 24-hour urinary collections: adjusted hazard ratios comparing the lowest quartile with the highest quartile were 3.05 (95% confidence interval, 1.54 to 6.04) for 24-hour urinary potassium excretion, 1.95 (95% confidence interval, 1.05 to 3.62) for spot urinary potassium-to-creatinine ratio, and 3.79 (95% confidence interval, 1.51 to 9.51) for spot urinary potassium concentration. CONCLUSIONS: Low urinary potassium excretion is associated with progression of CKD. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | American Society of Nephrology | - |
dc.relation.isPartOf | CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Urinary Potassium Excretion and Progression of CKD | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Hyung Woo Kim | - |
dc.contributor.googleauthor | Jung Tak Park | - |
dc.contributor.googleauthor | Tae-Hyun Yoo | - |
dc.contributor.googleauthor | Joongyub Lee | - |
dc.contributor.googleauthor | Wookyung Chung | - |
dc.contributor.googleauthor | Kyu-Beck Lee | - |
dc.contributor.googleauthor | Dong-Wan Chae | - |
dc.contributor.googleauthor | Curie Ahn | - |
dc.contributor.googleauthor | Shin-Wook Kang | - |
dc.contributor.googleauthor | Kyu Hun Choi | - |
dc.contributor.googleauthor | Seung Hyeok Han | - |
dc.identifier.doi | 10.2215/CJN.07820618 | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A01151 | - |
dc.contributor.localId | A01654 | - |
dc.contributor.localId | A02526 | - |
dc.contributor.localId | A04043 | - |
dc.contributor.localId | A04304 | - |
dc.relation.journalcode | J00584 | - |
dc.identifier.eissn | 1555-905X | - |
dc.identifier.pmid | 30765533 | - |
dc.identifier.url | https://cjasn.asnjournals.org/content/14/3/330.long | - |
dc.subject.keyword | Confidence Intervals | - |
dc.subject.keyword | Disease Progression | - |
dc.subject.keyword | Follow-Up Studies | - |
dc.subject.keyword | Kidney Failure, Chronic | - |
dc.subject.keyword | Potassium | - |
dc.subject.keyword | Proportional Hazards Models | - |
dc.subject.keyword | Renal Insufficiency, Chronic | - |
dc.subject.keyword | Urinary potassium excretion | - |
dc.subject.keyword | chronic kidney disease | - |
dc.subject.keyword | creatinine | - |
dc.subject.keyword | glomerular filtration rate | - |
dc.subject.keyword | kidney | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | 강신욱 | - |
dc.contributor.affiliatedAuthor | 김형우 | - |
dc.contributor.affiliatedAuthor | 박정탁 | - |
dc.contributor.affiliatedAuthor | 유태현 | - |
dc.contributor.affiliatedAuthor | 최규헌 | - |
dc.contributor.affiliatedAuthor | 한승혁 | - |
dc.citation.volume | 14 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 330 | - |
dc.citation.endPage | 340 | - |
dc.identifier.bibliographicCitation | CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol.14(3) : 330-340, 2019 | - |
dc.identifier.rimsid | 62481 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.