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The Effect on Bone Outcomes of Home-based Exercise Intervention for Prostate Cancer Survivors Receiving Androgen Deprivation Therapy: A Pilot Randomized Controlled Trial
DC Field | Value | Language |
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dc.contributor.author | 최영득 | - |
dc.date.accessioned | 2019-05-29T05:06:18Z | - |
dc.date.available | 2019-05-29T05:06:18Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0162-220X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/169402 | - |
dc.description.abstract | BACKGROUND: Cancer treatment-induced bone loss has important long-term effects in prostate cancer survivors (PCSs) receiving androgen deprivation therapy (ADT), but little is known about preventive interventions. OBJECTIVE: The aim of this study was to examine the feasibility and preliminary effectiveness of a 6-month home-based exercise intervention in PCSs. METHODS: In this pilot, randomized controlled trial, 51 men (mean age, 70.8 years) were randomized to a 6-month home-based exercise intervention for preventing osteoporosis group (n = 26) or an exercise placebo intervention of stretching exercise group (n = 25). Primary outcomes were bone mineral density and bone turnover markers. Secondary outcomes were physical performance (level of physical activity, muscle strength, and balance) and health-related quality of life. RESULTS: The patient retention rate for 6 months was 80.4%. The mean adherence rate was 84.7% for weight-bearing exercise and 64.8% for resistance exercise. No adverse events during the study period were reported. Although primary outcomes did not differ significantly between the 2 groups, the home-based exercise intervention for preventing osteoporosis group demonstrated significantly greater increased muscle strength than the stretching exercise group. CONCLUSIONS: A home-based exercise program is relatively feasible and safe and may improve muscle strength but not bone outcomes. IMPLICATIONS FOR PRACTICE: Given the importance of preventing cancer treatment-induced bone loss among PCSs receiving ADT, a home-based exercise intervention can be considered, but further trials with a larger sample are required to determine its effect for bone outcomes. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | CANCER NURSING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | The Effect on Bone Outcomes of Home-based Exercise Intervention for Prostate Cancer Survivors Receiving Androgen Deprivation Therapy: A Pilot Randomized Controlled Trial | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨의학교실) | - |
dc.contributor.googleauthor | Kim, Soo Hyun | - |
dc.contributor.googleauthor | Seong, Do Hwan | - |
dc.contributor.googleauthor | Yoon, Sang Min | - |
dc.contributor.googleauthor | Choi, Young Deuk | - |
dc.contributor.googleauthor | Choi, Eunju | - |
dc.contributor.googleauthor | Song, Youngkyu | - |
dc.contributor.googleauthor | Song, Hosook | - |
dc.identifier.doi | 10.1097/NCC.0000000000000530 | - |
dc.contributor.localId | A04111 | - |
dc.relation.journalcode | J00450 | - |
dc.identifier.eissn | 1538-9804 | - |
dc.identifier.pmid | 28731882 | - |
dc.identifier.url | https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00002820-201809000-00004&LSLINK=80&D=ovft | - |
dc.contributor.alternativeName | Choi, Young Deuk | - |
dc.contributor.affiliatedAuthor | 최영득 | - |
dc.citation.volume | 41 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 379 | - |
dc.citation.endPage | 388 | - |
dc.identifier.bibliographicCitation | CANCER NURSING, Vol.41(5) : 379-388, 2018 | - |
dc.identifier.rimsid | 59090 | - |
dc.type.rims | ART | - |
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