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The Effect on Bone Outcomes of Home-based Exercise Intervention for Prostate Cancer Survivors Receiving Androgen Deprivation Therapy: A Pilot Randomized Controlled Trial

DC FieldValueLanguage
dc.contributor.author최영득-
dc.date.accessioned2019-05-29T05:06:18Z-
dc.date.available2019-05-29T05:06:18Z-
dc.date.issued2018-
dc.identifier.issn0162-220X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/169402-
dc.description.abstractBACKGROUND: Cancer treatment-induced bone loss has important long-term effects in prostate cancer survivors (PCSs) receiving androgen deprivation therapy (ADT), but little is known about preventive interventions. OBJECTIVE: The aim of this study was to examine the feasibility and preliminary effectiveness of a 6-month home-based exercise intervention in PCSs. METHODS: In this pilot, randomized controlled trial, 51 men (mean age, 70.8 years) were randomized to a 6-month home-based exercise intervention for preventing osteoporosis group (n = 26) or an exercise placebo intervention of stretching exercise group (n = 25). Primary outcomes were bone mineral density and bone turnover markers. Secondary outcomes were physical performance (level of physical activity, muscle strength, and balance) and health-related quality of life. RESULTS: The patient retention rate for 6 months was 80.4%. The mean adherence rate was 84.7% for weight-bearing exercise and 64.8% for resistance exercise. No adverse events during the study period were reported. Although primary outcomes did not differ significantly between the 2 groups, the home-based exercise intervention for preventing osteoporosis group demonstrated significantly greater increased muscle strength than the stretching exercise group. CONCLUSIONS: A home-based exercise program is relatively feasible and safe and may improve muscle strength but not bone outcomes. IMPLICATIONS FOR PRACTICE: Given the importance of preventing cancer treatment-induced bone loss among PCSs receiving ADT, a home-based exercise intervention can be considered, but further trials with a larger sample are required to determine its effect for bone outcomes.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherLippincott Williams & Wilkins-
dc.relation.isPartOfCANCER NURSING-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleThe Effect on Bone Outcomes of Home-based Exercise Intervention for Prostate Cancer Survivors Receiving Androgen Deprivation Therapy: A Pilot Randomized Controlled Trial-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨의학교실)-
dc.contributor.googleauthorKim, Soo Hyun-
dc.contributor.googleauthorSeong, Do Hwan-
dc.contributor.googleauthorYoon, Sang Min-
dc.contributor.googleauthorChoi, Young Deuk-
dc.contributor.googleauthorChoi, Eunju-
dc.contributor.googleauthorSong, Youngkyu-
dc.contributor.googleauthorSong, Hosook-
dc.identifier.doi10.1097/NCC.0000000000000530-
dc.contributor.localIdA04111-
dc.relation.journalcodeJ00450-
dc.identifier.eissn1538-9804-
dc.identifier.pmid28731882-
dc.identifier.urlhttps://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00002820-201809000-00004&LSLINK=80&D=ovft-
dc.contributor.alternativeNameChoi, Young Deuk-
dc.contributor.affiliatedAuthor최영득-
dc.citation.volume41-
dc.citation.number5-
dc.citation.startPage379-
dc.citation.endPage388-
dc.identifier.bibliographicCitationCANCER NURSING, Vol.41(5) : 379-388, 2018-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

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