Cited 29 times in
Effect of Androgen-Deprivation Therapy on Bone Mineral Density in Patients with Prostate Cancer: A Systematic Review and Meta-Analysis
DC Field | Value | Language |
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dc.contributor.author | 구교철 | - |
dc.contributor.author | 김광준 | - |
dc.contributor.author | 김도경 | - |
dc.contributor.author | 이주용 | - |
dc.contributor.author | 조강수 | - |
dc.contributor.author | 하윤수 | - |
dc.contributor.author | 홍남기 | - |
dc.date.accessioned | 2019-04-03T07:49:30Z | - |
dc.date.available | 2019-04-03T07:49:30Z | - |
dc.date.issued | 2019 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167759 | - |
dc.description.abstract | We aimed to evaluate the change in bone mineral density (BMD) in patients with prostate cancer (PCa) receiving androgen deprivation therapy (ADT) compared to those with PCa or other urologic conditions not receiving ADT. Literature searches were conducted throughout October 2018. The eligibility of each study was assessed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines using the Participant, Intervention, Comparator, Outcome, and Study design method. The outcomes analyzed were the mean difference (MD) of percent changes in BMD of lumbar spine, femur neck, and total hip. Five prospective cohort studies with a total of 533 patients were included in the present study. Statistically significant decreases of BMD change relative to the control group were observed in the ADT treatment group in the lumbar spine (MD -3.60, 95% CI -6.72 to -0.47, P = 0.02), femoral neck (MD -3.11, 95% CI -4.73 to -1.48, P = 0.0002), and total hip (MD -1.59, 95% CI -2.99 to -0.19, P = 0.03). There is a significant relationship between ADT and BMD reduction in patients with PCa. Regular BMD testing and the optimal treatment for BMD loss should, therefore, be considered in patients with PCa undergoing ADT. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI AG | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Effect of Androgen-Deprivation Therapy on Bone Mineral Density in Patients with Prostate Cancer: A Systematic Review and Meta-Analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨의학교실) | - |
dc.contributor.googleauthor | Do Kyung Kim | - |
dc.contributor.googleauthor | Joo Yong Lee | - |
dc.contributor.googleauthor | Kwang Joon Kim | - |
dc.contributor.googleauthor | Namki Hong | - |
dc.contributor.googleauthor | Jong Won Kim | - |
dc.contributor.googleauthor | Yoon Soo Hah | - |
dc.contributor.googleauthor | Kyo Chul Koo | - |
dc.contributor.googleauthor | Jae Heon Kim | - |
dc.contributor.googleauthor | Kang Su Cho | - |
dc.identifier.doi | 10.3390/jcm8010113 | - |
dc.contributor.localId | A00188 | - |
dc.contributor.localId | A00317 | - |
dc.contributor.localId | A05453 | - |
dc.contributor.localId | A03161 | - |
dc.contributor.localId | A03801 | - |
dc.contributor.localId | A05526 | - |
dc.contributor.localId | A04388 | - |
dc.relation.journalcode | J03556 | - |
dc.identifier.eissn | 2077-0383 | - |
dc.identifier.pmid | 30669289 | - |
dc.subject.keyword | androgen deprivation therapy | - |
dc.subject.keyword | bone mineral density | - |
dc.subject.keyword | meta-analysis | - |
dc.subject.keyword | prostate cancer | - |
dc.subject.keyword | systematic review | - |
dc.contributor.alternativeName | Koo, Kyo Chul | - |
dc.contributor.affiliatedAuthor | 구교철 | - |
dc.contributor.affiliatedAuthor | 김광준 | - |
dc.contributor.affiliatedAuthor | 김도경 | - |
dc.contributor.affiliatedAuthor | 이주용 | - |
dc.contributor.affiliatedAuthor | 조강수 | - |
dc.contributor.affiliatedAuthor | 하윤수 | - |
dc.contributor.affiliatedAuthor | 홍남기 | - |
dc.citation.volume | 8 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | e113 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, Vol.8(1) : e113, 2019 | - |
dc.identifier.rimsid | 58356 | - |
dc.type.rims | ART | - |
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