Cited 64 times in
Increased Risk of Diabetes in Inflammatory Bowel Disease Patients: A Nationwide Population-based Study in Korea
DC Field | Value | Language |
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dc.contributor.author | 천재영 | - |
dc.date.accessioned | 2019-03-15T02:44:40Z | - |
dc.date.available | 2019-03-15T02:44:40Z | - |
dc.date.issued | 2019 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167643 | - |
dc.description.abstract | The association of diabetes with inflammatory bowel disease (IBD) remains unclear. The risk of diabetes in patients with IBD compared with non-IBD controls was investigated. Using the National Health Insurance database of South Korea, 8070 patients with IBD based on the International Classification of Disease 10th revision (ICD-10) codes and rare intractable disease codes for Crohn’s disease (CD) and ulcerative colitis (UC) were compared with 40,350 non-IBD individuals (2010–2014). Newly diagnosed diabetes identified using ICD-10 codes and the prescription of anti-diabetic medication by the end of the follow-up period (2016) was investigated. During a mean follow-up of 5.1 years, the incidence of diabetes in patients with IBD was significantly higher compared with controls after adjusting for serum glucose levels and steroid use (23.19 vs. 22.02 per 1000 person-years; hazard ratio (HR), 1.135; 95% confidence interval (CI), 1.048– 1.228). The risk of diabetes was significantly higher in patients with CD (HR, 1.677; 95% CI, 1.408– 1.997), but not in UC (HR, 1.061; 95% CI, 0.973–1.156). The effect of IBD on the development of diabetes was significantly more prominent in younger patients (p < 0.001). Patients with CD are at a higher risk of diabetes. Regular monitoring for diabetes is recommended, even in younger CD patients who do not use steroid medication. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | MDPI AG | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Increased Risk of Diabetes in Inflammatory Bowel Disease Patients: A Nationwide Population-based Study in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Eun Ae Kang | - |
dc.contributor.googleauthor | Kyungdo Han | - |
dc.contributor.googleauthor | Jaeyoung Chun | - |
dc.contributor.googleauthor | Hosim Soh | - |
dc.contributor.googleauthor | Seona Park | - |
dc.contributor.googleauthor | Jong Pil Im | - |
dc.contributor.googleauthor | Joo Sung Kim | - |
dc.identifier.doi | 10.3390/jcm8030343 | - |
dc.contributor.localId | A05701 | - |
dc.relation.journalcode | J03556 | - |
dc.identifier.eissn | 2077-0383 | - |
dc.subject.keyword | diabetes | - |
dc.subject.keyword | epidemiology | - |
dc.subject.keyword | inflammatory bowel disease | - |
dc.contributor.alternativeName | Cheon, Jae Young | - |
dc.contributor.affiliatedAuthor | 천재영 | - |
dc.citation.volume | 8 | - |
dc.citation.startPage | 343 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, Vol.8 : 343, 2019 | - |
dc.identifier.rimsid | 64729 | - |
dc.type.rims | ART | - |
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