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Increased Risk of Diabetes in Inflammatory Bowel Disease Patients: A Nationwide Population-based Study in Korea

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dc.contributor.author천재영-
dc.date.accessioned2019-03-15T02:44:40Z-
dc.date.available2019-03-15T02:44:40Z-
dc.date.issued2019-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/167643-
dc.description.abstractThe association of diabetes with inflammatory bowel disease (IBD) remains unclear. The risk of diabetes in patients with IBD compared with non-IBD controls was investigated. Using the National Health Insurance database of South Korea, 8070 patients with IBD based on the International Classification of Disease 10th revision (ICD-10) codes and rare intractable disease codes for Crohn’s disease (CD) and ulcerative colitis (UC) were compared with 40,350 non-IBD individuals (2010–2014). Newly diagnosed diabetes identified using ICD-10 codes and the prescription of anti-diabetic medication by the end of the follow-up period (2016) was investigated. During a mean follow-up of 5.1 years, the incidence of diabetes in patients with IBD was significantly higher compared with controls after adjusting for serum glucose levels and steroid use (23.19 vs. 22.02 per 1000 person-years; hazard ratio (HR), 1.135; 95% confidence interval (CI), 1.048– 1.228). The risk of diabetes was significantly higher in patients with CD (HR, 1.677; 95% CI, 1.408– 1.997), but not in UC (HR, 1.061; 95% CI, 0.973–1.156). The effect of IBD on the development of diabetes was significantly more prominent in younger patients (p < 0.001). Patients with CD are at a higher risk of diabetes. Regular monitoring for diabetes is recommended, even in younger CD patients who do not use steroid medication.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherMDPI AG-
dc.relation.isPartOfJOURNAL OF CLINICAL MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleIncreased Risk of Diabetes in Inflammatory Bowel Disease Patients: A Nationwide Population-based Study in Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorEun Ae Kang-
dc.contributor.googleauthorKyungdo Han-
dc.contributor.googleauthorJaeyoung Chun-
dc.contributor.googleauthorHosim Soh-
dc.contributor.googleauthorSeona Park-
dc.contributor.googleauthorJong Pil Im-
dc.contributor.googleauthorJoo Sung Kim-
dc.identifier.doi10.3390/jcm8030343-
dc.contributor.localIdA05701-
dc.relation.journalcodeJ03556-
dc.identifier.eissn2077-0383-
dc.subject.keyworddiabetes-
dc.subject.keywordepidemiology-
dc.subject.keywordinflammatory bowel disease-
dc.contributor.alternativeNameCheon, Jae Young-
dc.contributor.affiliatedAuthor천재영-
dc.citation.volume8-
dc.citation.startPage343-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL MEDICINE, Vol.8 : 343, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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