Cited 27 times in
Benefit of Prolonged Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stent for Coronary Bifurcation Lesions: Results From the Coronary Bifurcation Stenting Registry II
DC Field | Value | Language |
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dc.contributor.author | 장양수 | - |
dc.date.accessioned | 2019-03-15T02:39:47Z | - |
dc.date.available | 2019-03-15T02:39:47Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1941-7640 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167626 | - |
dc.description.abstract | BACKGROUND: Whether prolonged dual antiplatelet therapy (DAPT) improves clinical outcomes after percutaneous coronary intervention for coronary bifurcation lesion is uncertain. METHODS AND RESULTS: We evaluated 2082 patients who were treated with drug-eluting stent for bifurcation lesions and were event free (no death, myocardial infarction [MI], cerebrovascular accident, stent thrombosis, or any revascularization) at 12 months after the index procedure. Patients were divided into 2 groups: DAPT ≥12-month group (n=1776) and DAPT <12-month group (n=306). Primary outcome was all-cause death or MI. At 4 years after the index procedure, death or MI occurred less frequently in the DAPT ≥12-month group than the DAPT <12-month group (2.8% versus 12.3%; adjusted hazard ratio, 0.21; 95% confidence interval, 0.13-0.35; P<0.001). After propensity score matching, incidence of death or MI was still lower in the DAPT ≥12-month group than the DAPT <12-month group (2.6% versus 12.3%; adjusted hazard ratio, 0.22; 95% confidence interval, 0.12-0.38; P<0.001). In subgroup analysis, the treatment effect of prolonged DAPT was consistent across subgroups regardless of lesion location, stenting technique, or type of used drug-eluting stent. CONCLUSIONS: The risk of all-cause death or MI was significantly lower in the ≥12-month DAPT group than the <12-month DAPT group after percutaneous coronary intervention for bifurcation lesion using drug-eluting stent. Our results suggest that prolonged DAPT may improve long-term clinical outcomes after percutaneous coronary intervention for bifurcation lesions. CLINICAL TRIAL REGISTRATION: URL: https://www.clinicaltrials.gov. Unique identifier: NCT01642992. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | CIRCULATION-CARDIOVASCULAR INTERVENTIONS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Benefit of Prolonged Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stent for Coronary Bifurcation Lesions: Results From the Coronary Bifurcation Stenting Registry II | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Woo Jin Jang | - |
dc.contributor.googleauthor | Sung Gyun Ahn | - |
dc.contributor.googleauthor | Young Bin Song | - |
dc.contributor.googleauthor | Seung-Hyuk Choi | - |
dc.contributor.googleauthor | Woo Jung Chun | - |
dc.contributor.googleauthor | Ju Hyeon Oh | - |
dc.contributor.googleauthor | Sung Woo Cho | - |
dc.contributor.googleauthor | Bum Sung Kim | - |
dc.contributor.googleauthor | Jung Han Yoon | - |
dc.contributor.googleauthor | Bon-Kwon Koo | - |
dc.contributor.googleauthor | Cheol Woong Yu | - |
dc.contributor.googleauthor | Yang Soo Jang | - |
dc.contributor.googleauthor | Seung-Jea Tahk | - |
dc.contributor.googleauthor | Hyo-Soo Kim | - |
dc.contributor.googleauthor | Hyeon-Cheol Gwon | - |
dc.contributor.googleauthor | Sung Yun Lee | - |
dc.contributor.googleauthor | Joo-Yong Hahn | - |
dc.identifier.doi | 10.1161/CIRCINTERVENTIONS.117.005849 | - |
dc.contributor.localId | A03448 | - |
dc.relation.journalcode | J00539 | - |
dc.identifier.eissn | 1941-7632 | - |
dc.identifier.pmid | 30006330 | - |
dc.identifier.url | http://www.ahajournals.org/doi/full/10.1161/CIRCINTERVENTIONS.117.005849 | - |
dc.subject.keyword | drug-eluting stents | - |
dc.subject.keyword | incidence | - |
dc.subject.keyword | myocardial infarction | - |
dc.subject.keyword | percutaneous coronary intervention | - |
dc.subject.keyword | thrombosis | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | 장양수 | - |
dc.citation.volume | 11 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | e005849 | - |
dc.identifier.bibliographicCitation | CIRCULATION-CARDIOVASCULAR INTERVENTIONS, Vol.11(7) : e005849, 2018 | - |
dc.identifier.rimsid | 61045 | - |
dc.type.rims | ART | - |
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