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Prediction of organ-confined disease after robot-assisted radical prostatectomy in patients with clinically locally-advanced prostate cancer
DC Field | Value | Language |
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dc.contributor.author | 이주용 | - |
dc.contributor.author | 정해도 | - |
dc.contributor.author | 조강수 | - |
dc.contributor.author | 최영득 | - |
dc.contributor.author | 함원식 | - |
dc.date.accessioned | 2019-03-15T02:38:49Z | - |
dc.date.available | 2019-03-15T02:38:49Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1015-9584 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167624 | - |
dc.description.abstract | BACKGROUND: Little is known about the preoperative predictive factors that could identify subsets of favorable patients who can be possibly cured with robot-assisted radical prostatectomy (RARP) alone in locally advanced prostate cancer (LAPCa). Our study was designed to identify clinical predictors of pathologic organ-confined disease (pOCD) in RARP setting. METHODS: Between 2007 and 2013, clinicopathological and oncological data from 273 consecutive men undergoing robot-assisted RP with extended PLND for clinically LAPCa were reviewed in a single-institution, retrospectively. After exclusion of patients who received neoadjuvant hormone treatment before surgery, 186 subjects satisfied the final inclusion criteria. RESULTS: Fourty-three patients (23.1% of total cohort) with preoperative clinically LAPCa patients were down-staged to pOCD following RARP. Preoperative prostate-specific antigen (PSA) level, preoperative PSAD, positive core percent, maximal tumor volume in any core, and biopsy Gleason score were significantly associated with down-staging into pOCD following RARP. Multivariate logistic regression analysis revealed that lower preoperative PSA (≤10 ng/mL) and maximal tumor volume in any core (≤70%) were independent predictors of pOCD following RARP. CONCLUSIONS: Approximately 23% of preoperative clinically LAPCa patients were down-staged to pOCD following RARP. Preoperative PSA and maximal tumor volume in any biopsy core might be useful clinical predictors of pOCD in clinically LAPCa patients in RARP setting. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Excerpta Media Asia | - |
dc.relation.isPartOf | ASIAN JOURNAL OF SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | Biopsy, Large-Core Needle | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Forecasting | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Logistic Models | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoadjuvant Therapy | - |
dc.subject.MESH | Neoplasm Grading | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Preoperative Care | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Prostate-Specific Antigen | - |
dc.subject.MESH | Prostatectomy/methods* | - |
dc.subject.MESH | Prostatic Neoplasms/diagnosis | - |
dc.subject.MESH | Prostatic Neoplasms/pathology* | - |
dc.subject.MESH | Prostatic Neoplasms/surgery* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Robotic Surgical Procedures/methods* | - |
dc.title | Prediction of organ-confined disease after robot-assisted radical prostatectomy in patients with clinically locally-advanced prostate cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨의학교실) | - |
dc.contributor.googleauthor | Ho Won Kang | - |
dc.contributor.googleauthor | Hae Do Jung | - |
dc.contributor.googleauthor | Joo Yong Lee | - |
dc.contributor.googleauthor | Jong Kyou Kwon | - |
dc.contributor.googleauthor | Seong Uk Jeh | - |
dc.contributor.googleauthor | Kang Su Cho | - |
dc.contributor.googleauthor | Won Sik Ham | - |
dc.contributor.googleauthor | Young Deuk Choi | - |
dc.identifier.doi | 10.1016/j.asjsur.2017.10.005 | - |
dc.contributor.localId | A03161 | - |
dc.contributor.localId | A03759 | - |
dc.contributor.localId | A03801 | - |
dc.contributor.localId | A04111 | - |
dc.contributor.localId | A04337 | - |
dc.relation.journalcode | J03114 | - |
dc.identifier.eissn | 0219-3108 | - |
dc.identifier.pmid | 29274670 | - |
dc.subject.keyword | Prostatectomy | - |
dc.subject.keyword | Prostatic neoplasms | - |
dc.subject.keyword | Robotics | - |
dc.subject.keyword | Treatment outcome | - |
dc.contributor.alternativeName | Lee, Joo Yong | - |
dc.contributor.affiliatedAuthor | 이주용 | - |
dc.contributor.affiliatedAuthor | 정해도 | - |
dc.contributor.affiliatedAuthor | 조강수 | - |
dc.contributor.affiliatedAuthor | 최영득 | - |
dc.contributor.affiliatedAuthor | 함원식 | - |
dc.citation.volume | 42 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 120 | - |
dc.citation.endPage | 125 | - |
dc.identifier.bibliographicCitation | ASIAN JOURNAL OF SURGERY, Vol.42(1) : 120-125, 2019 | - |
dc.identifier.rimsid | 61043 | - |
dc.type.rims | ART | - |
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