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Consistency of quantitative analysis of coronary computed tomography angiography

Authors
 Sang-Eun Lee  ;  Hyung-Bok Park  ;  Dongchun Xuan  ;  Byoung Kwon Lee  ;  Myeong-Ki Hong  ;  Yangsoo Jang  ;  Hyuk-Jae Chang 
Citation
 JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY, Vol.13(1) : 48-54, 2019 
Journal Title
 JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY 
ISSN
 1934-5925 
Issue Date
2019
Keywords
Coronary artery disease ; Coronary computed tomography angiography ; Coronary plaque ; Plaque volume ; Quantitative assessment
Abstract
BACKGROUND: The present study aimed to assess the reliability and reproducibility of coronary computed tomography angiography (CCTA) for the serial quantitative assessment of plaque volume. METHODS: Patients who underwent repeated CCTA scans within 90 days were retrospectively screened and enrolled. Clinical data and CCTA imaging data were collected. Paired CCTA scans were analyzed using the quantitative method by separate observers blinded to the other paired CCTA scans. Results were compared between the index CCTA and follow-up CCTA. RESULTS: Paired CT scans of 95 patients (61 ± 13 years; 56.8% men) with same tube voltages (kVp) at both CCTAs and 24 patients (57 ± 19 years; 48.3% men) with different kVp at two CCTAs were analyzed. In patients with same kVp at both CCTAs, there were no difference in PV and PVs of each components in per-segment analysis and per-lesion analysis (all p > 0.05). In per-lesion analysis of CCTAs from patients who used different kVp between two CCTAs, lesion length, area and diameter stenosis, and PVs were not different between index and follow-up CCTAs (all p > 0.05). Segment length and PV were also showed no difference between two serial CCTAs in per-segment analysis. CONCLUSION: We showed the reproducibility and reliability of quantitative analysis of CCTA for assessment of coronary plaques. CCTA can be applied for the serial quantitative assessment of coronary artery disease progression, regardless of differences in the image acquisition protocol.
Full Text
https://www.sciencedirect.com/science/article/pii/S1934592518300911
DOI
10.1016/j.jcct.2018.09.012
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Byoung Kwon(이병권) ORCID logo https://orcid.org/0000-0001-9259-2776
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Chang, Hyuk-Jae(장혁재) ORCID logo https://orcid.org/0000-0002-6139-7545
Hong, Myeong Ki(홍명기) ORCID logo https://orcid.org/0000-0002-2090-2031
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/167616
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