Cited 5 times in
Cancer Risk in Patients with Intestinal Behçet’s Disease: A Nationwide Population-Based Study
DC Field | Value | Language |
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dc.contributor.author | 김원호 | - |
dc.contributor.author | 천재희 | - |
dc.contributor.author | 한민경 | - |
dc.contributor.author | 박소희 | - |
dc.date.accessioned | 2019-03-15T02:28:15Z | - |
dc.date.available | 2019-03-15T02:28:15Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167501 | - |
dc.description.abstract | Background/Aims: The relationship between intestinal Behçet's disease (BD) and cancer remains unclear. We conducted a nationwide, population-based study to determine the risk of cancer in patients with intestinal BD. Methods: Using the National Health Insurance claims records, we collected data on 365 patients who had been diagnosed with intestinal BD between 2011 and 2014. Standardized incidence ratios (SIRs) of overall and site-specific cancers in patients with intestinal BD in comparison with the general population were calculated. Results: Among 167 men with intestinal BD, four cases of cancer were observed; among 191 women with BD, eight cases of cancer were observed. The risk of all cancers was significantly higher in women with intestinal BD than in women of the general population (SIR, 4.27; 95% confidence interval [CI], 1.84 to 8.41). However, in men with intestinal BD, the risk of all cancers was not significantly higher than that in men of the general population (SIR, 2.08; 95% CI, 0.57 to 5.33). The risk of hematologic cancer was significantly higher in both men and women with intestinal BD than in their counterparts in the general population (SIR, 23.90; 95% CI, 2.89 to 86.32 in men; SIR, 34.47; 95% CI, 4.17 to 124.51 in women). In particular, patients with intestinal BD showed a higher risk of leukemia and myelodysplastic syndrome than the general population. Conclusions: Patients with intestinal BD demonstrated a higher risk of hematologic cancer, especially leukemia, than the general population. Furthermore, women with intestinal BD showed a higher risk of all cancers. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Editorial Office of Gut and Liver | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Behcet Syndrome/complications* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hematologic Neoplasms/epidemiology | - |
dc.subject.MESH | Hematologic Neoplasms/etiology* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Intestinal Diseases/complications* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasms/epidemiology | - |
dc.subject.MESH | Neoplasms/etiology | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Sex Factors | - |
dc.title | Cancer Risk in Patients with Intestinal Behçet’s Disease: A Nationwide Population-Based Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Minkyung Han | - |
dc.contributor.googleauthor | Yoon Suk Jung | - |
dc.contributor.googleauthor | Won Ho Kim | - |
dc.contributor.googleauthor | Jae Hee Cheon | - |
dc.contributor.googleauthor | Sohee Park | - |
dc.identifier.doi | 10.5009/gnl17324 | - |
dc.contributor.localId | A00774 | - |
dc.contributor.localId | A04030 | - |
dc.contributor.localId | A05436 | - |
dc.relation.journalcode | J00954 | - |
dc.identifier.eissn | 2005-1212 | - |
dc.identifier.pmid | 29429154 | - |
dc.subject.keyword | Intestinal Behçet’s disease | - |
dc.subject.keyword | Neoplasms | - |
dc.subject.keyword | Population-based | - |
dc.contributor.alternativeName | Kim, Won Ho | - |
dc.contributor.affiliatedAuthor | 김원호 | - |
dc.contributor.affiliatedAuthor | 천재희 | - |
dc.contributor.affiliatedAuthor | 한민경 | - |
dc.citation.volume | 12 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 433 | - |
dc.citation.endPage | 439 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, Vol.12(4) : 433-439, 2018 | - |
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