Cited 5 times in
Extensive Disease Subtypes in Adult Patients with Ulcerative Colitis: Non-pancolitis Versus Pancolitis.
DC Field | Value | Language |
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dc.contributor.author | 김원호 | - |
dc.contributor.author | 김태일 | - |
dc.contributor.author | 박수정 | - |
dc.contributor.author | 박예현 | - |
dc.contributor.author | 천재희 | - |
dc.date.accessioned | 2019-03-15T02:28:09Z | - |
dc.date.available | 2019-03-15T02:28:09Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0163-2116 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167499 | - |
dc.description.abstract | BACKGROUND AND AIM: Few studies have compared pancolitis and non-pancolitis E3 in adult patients with ulcerative colitis (UC). This study aimed to evaluate the natural disease courses and factors affecting outcomes between pancolitis and non-pancolitis E3. METHODS: We retrospectively analyzed 117 patients, including 93 with extensive colitis (E3) and 24 with UC confined to the rectum or left-sided colon and appendiceal orifice inflammation at the time of diagnosis, who were regularly followed up for at least 1 year. Patients with E3 were divided into two groups according to the degree of disease extension: pancolitis group (disease extent up to the cecum or proximal ascending colon) and non-pancolitis E3 group (disease extent above the splenic flexure but not up to the proximal ascending colon). Clinical findings at diagnosis; comorbidity; medications; Mayo score; cumulative rates of corticosteroid, immunomodulator, and anti-tumor necrosis factor (anti-TNF) alpha use; relapse; and admission were compared between the pancolitis and non-pancolitis E3 groups. RESULTS: The median follow-up duration of the 117 patients was 74 (range 15-158) months. Fifty-one patients (43.5%) had pancolitis. The Mayo score at initial diagnosis, cumulative relapse rate, and cumulative admission rate were significantly higher in the pancolitis group than in the non-pancolitis E3 group (P < 0.001, P = 0.023 and P = 0.007, respectively). However, there was no significant difference between the groups in the rates of cumulative immunomodulator and anti-TNF alpha use (P = 0.67 and P = 0.73, respectively). CONCLUSIONS: In patients with extensive UC (E3), pancolitis was associated with higher probabilities of cumulative relapse or admission, indicating poor prognosis. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer Science + Business Media | - |
dc.relation.isPartOf | DIGESTIVE DISEASES AND SCIENCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Extensive Disease Subtypes in Adult Patients with Ulcerative Colitis: Non-pancolitis Versus Pancolitis. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Dong Suk Shin | - |
dc.contributor.googleauthor | Jae Hee Cheon | - |
dc.contributor.googleauthor | Yong Eun Park | - |
dc.contributor.googleauthor | Yehyun Park | - |
dc.contributor.googleauthor | Soo Jung Park | - |
dc.contributor.googleauthor | Tae Il Kim | - |
dc.contributor.googleauthor | Won Ho Kim | - |
dc.identifier.doi | 10.1007/s10620-018-5218-x | - |
dc.contributor.localId | A00774 | - |
dc.contributor.localId | A01079 | - |
dc.contributor.localId | A01539 | - |
dc.contributor.localId | A01575 | - |
dc.contributor.localId | A04030 | - |
dc.relation.journalcode | J00737 | - |
dc.identifier.eissn | 1573-2568 | - |
dc.identifier.pmid | 30145694 | - |
dc.identifier.url | https://link.springer.com/article/10.1007%2Fs10620-018-5218-x | - |
dc.subject.keyword | Classification | - |
dc.subject.keyword | Disease extension | - |
dc.subject.keyword | Prognosis | - |
dc.subject.keyword | Ulcerative colitis | - |
dc.contributor.alternativeName | Kim, Won Ho | - |
dc.contributor.affiliatedAuthor | 김원호 | - |
dc.contributor.affiliatedAuthor | 김태일 | - |
dc.contributor.affiliatedAuthor | 박수정 | - |
dc.contributor.affiliatedAuthor | 박예현 | - |
dc.contributor.affiliatedAuthor | 천재희 | - |
dc.citation.volume | 63 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 3097 | - |
dc.citation.endPage | 3104 | - |
dc.identifier.bibliographicCitation | DIGESTIVE DISEASES AND SCIENCES, Vol.63(11) : 3097-3104, 2018 | - |
dc.identifier.rimsid | 41182 | - |
dc.type.rims | ART | - |
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