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수면 뇌파-기능자기공명영상 동기화 측정과 신호처리 기법을 통한 수면 단계별 뇌연결망 연구

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dc.contributor.author박해정-
dc.date.accessioned2019-02-14T01:56:02Z-
dc.date.available2019-02-14T01:56:02Z-
dc.date.issued2018-
dc.identifier.issn1225-7354-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/167300-
dc.description.abstractObjectives: Synchronous electroencephalogram (EEG) and functional magnetic resonance imaging (fMRI) has been used to explore sleep stage dependent functional brain networks. Despite a growing number of sleep studies using EEG-fMRI, few stud- ies have conducted network analysis on whole night sleep due to dif culty in data acquisition, artifacts, and sleep management within the MRI scanner. Methods: In order to perform network analysis for whole night sleep, we proposed experimental procedures and data process- ing techniques for EEG-fMRI. We acquired 6-7 hours of EEG-fMRI data per participant and conducted signal processing to re- duce artifacts in both EEG and fMRI. We then generated a functional brain atlas with 68 brain regions using independent com- ponent analysis of sleep fMRI data. Using this functional atlas, we constructed sleep level dependent functional brain networks. Results: When we evaluated functional connectivity distribution, sleep showed signi cantly reduced functional connectivity for the whole brain compared to that during wakefulness. REM sleep showed statistically different connectivity patterns compared to non-REM sleep in sleep-related subcortical brain circuits. Conclusion: This study suggests the feasibility of exploring functional brain networks using sleep EEG-fMRI for whole night sleep via appropriate experimental procedures and signal processing techniques for fMRI and EEG.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageKorean-
dc.publisherKOREAN ACADEMY OF SLEEP MEDICINE-
dc.relation.isPartOfSleep Medicine and Psychophysiology (수면정신생리)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title수면 뇌파-기능자기공명영상 동기화 측정과 신호처리 기법을 통한 수면 단계별 뇌연결망 연구-
dc.title.alternativeThe Feasibility for Whole-Night Sleep Brain Network Research Using Synchronous EEG-fMRI-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Nuclear Medicine (핵의학교실)-
dc.contributor.googleauthor김중일-
dc.contributor.googleauthor박범희-
dc.contributor.googleauthor윤탁-
dc.contributor.googleauthor박해정-
dc.identifier.doi10.14401/KASMED.2018.25.2.82-
dc.contributor.localIdA01730-
dc.relation.journalcodeJ03378-
dc.subject.keywordSleep-
dc.subject.keywordEEG-
dc.subject.keywordResting state fMRI-
dc.subject.keywordEEG-fMRI-
dc.subject.keywordBrain network-
dc.subject.keywordFunctional connectivity-
dc.contributor.alternativeNamePark, Hae Jeong-
dc.contributor.affiliatedAuthor박해정-
dc.citation.volume25-
dc.citation.number2-
dc.citation.startPage82-
dc.citation.endPage91-
dc.identifier.bibliographicCitationSleep Medicine and Psychophysiology (수면정신생리), Vol.25(2) : 82-91, 2018-
dc.identifier.rimsid61502-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers

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