Cited 9 times in
Metabolic syndrome, not menopause, is a risk factor for hypertension in peri-menopausal women
DC Field | Value | Language |
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dc.contributor.author | 김현창 | - |
dc.contributor.author | 박성하 | - |
dc.date.accessioned | 2019-02-14T01:54:55Z | - |
dc.date.available | 2019-02-14T01:54:55Z | - |
dc.date.issued | 2018 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167289 | - |
dc.description.abstract | Background: It has been long debated whether menopause itself is a risk factor for hypertension in peri-menopausal women. We aimed to assess the association between menopause and hypertension, and whether metabolic syndrome (MetS) has an influence on its effect. Methods: Data for 1502 women aged 42 to 53 from the Korean Genome and Epidemiology Study (KoGES) database were retrospectively analyzed. The KoGES database consists of 10,038 participants, of which 52.6% (5275) were female. Subjects were followed up for 4 years, and compared according to menopausal status. Additionally, 1216 non-hypertensive subjects were separately analyzed to assess whether a change in menopausal status was associated with development of hypertension. Results: The prevalence of hypertension, diabetes, and MetS for menopausal and non-menopausal subjects at baseline was 24.4% vs. 16.7%, 5.8% vs. 2.9%, and 25.4% vs. 16.6%, respectively (p < 0.01 for all comparisons). Among non-hypertensive subjects at baseline, prevalence of hypertension at 4-year follow-up was 9.4%, 19.7%, and 13.1% for non-menopausal, those who became menopause during follow-up, and those who were menopause at baseline, respectively. Development of hypertension was positively correlated with MetS (HR 3.90, 95% CI 2.51-6.07) and increased BMI (HR 1.09, 95% CI 1.03-1.16), while association with menopause was not significant. Conclusions: Menopause is closely associated with increased incidence of hypertension, but the increase may not be attributable to menopause itself but to increased prevalence of MetS. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Biomed Central | - |
dc.relation.isPartOf | Clinical Hypertension | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Metabolic syndrome, not menopause, is a risk factor for hypertension in peri-menopausal women | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine and Public Health (예방의학교실) | - |
dc.contributor.googleauthor | Gyu Chul Oh | - |
dc.contributor.googleauthor | Kee Soo Kang | - |
dc.contributor.googleauthor | Chan Soon Park | - |
dc.contributor.googleauthor | Ho Kyung Sung | - |
dc.contributor.googleauthor | Kyoung Hwa Ha | - |
dc.contributor.googleauthor | Hyeon Chang Kim | - |
dc.contributor.googleauthor | Sungha Park | - |
dc.contributor.googleauthor | Sang Hyun Ihm | - |
dc.contributor.googleauthor | Hae-Young Lee | - |
dc.identifier.doi | 10.1186/s40885-018-0099-z | - |
dc.contributor.localId | A01142 | - |
dc.contributor.localId | A01512 | - |
dc.relation.journalcode | J02982 | - |
dc.identifier.eissn | 2056-5909 | - |
dc.identifier.pmid | 30349737 | - |
dc.subject.keyword | Hypertension | - |
dc.subject.keyword | Menopause | - |
dc.subject.keyword | Metabolic syndrome | - |
dc.subject.keyword | Obesity | - |
dc.contributor.alternativeName | Kim, Hyeon Chang | - |
dc.contributor.affiliatedAuthor | 김현창 | - |
dc.contributor.affiliatedAuthor | 박성하 | - |
dc.citation.volume | 24 | - |
dc.citation.startPage | 14 | - |
dc.identifier.bibliographicCitation | Clinical Hypertension, Vol.24 : 14, 2018 | - |
dc.identifier.rimsid | 61493 | - |
dc.type.rims | ART | - |
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