Cited 14 times in
Severe vitamin D deficiency is a risk factor for renal hyperfiltration
DC Field | Value | Language |
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dc.contributor.author | 강신욱 | - |
dc.contributor.author | 기연경 | - |
dc.contributor.author | 김형래 | - |
dc.contributor.author | 남기헌 | - |
dc.contributor.author | 박서현 | - |
dc.contributor.author | 박정탁 | - |
dc.contributor.author | 안성영 | - |
dc.contributor.author | 유태현 | - |
dc.contributor.author | 윤해룡 | - |
dc.contributor.author | 이미솔 | - |
dc.contributor.author | 차민욱 | - |
dc.contributor.author | 한승혁 | - |
dc.date.accessioned | 2019-02-12T16:40:43Z | - |
dc.date.available | 2019-02-12T16:40:43Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0002-9165 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167085 | - |
dc.description.abstract | Background: Vitamin D deficiency is associated with renal progression in chronic kidney disease. Moreover, improvement of clinical outcomes after vitamin D supplementation has been reported in the diabetic and chronic kidney disease population. Objective: We investigated the association between renal hyperfiltration (RHF) and vitamin D status in a relatively healthy population. Design: Data were retrieved from the Korean NHANES, a nationwide population-based cross-sectional study from 2008 to 2015. Overall, 33,210 subjects with normal renal function were included in the final analysis. Severe vitamin D deficiency was defined as serum 25-hydroxyvitamin D concentration <10 ng/mL. RHF was defined as estimated glomerular filtration rate with residual in the >95th percentile after adjustment for age, sex, height, weight, and history of hypertension or diabetes. Results: The mean ± SD age of subjects was 48.1 ± 15.9 y, and the number of women was 18,779 (56.5%). Estimated glomerular filtration rate was negatively associated with serum 25-hydroxyvitamin D concentrations in multivariable linear regression analysis (β: -0.02; 95% CI: -0.02, -0.01; P < 0.001). Furthermore, 1637 (4.9%) subjects were categorized into the RHF group, and the prevalence of RHF was significantly higher in the severe vitamin D deficiency group than in the sufficiency group (5.8% compared with 5.0%, P < 0.001). In a multivariable logistic regression model, severe vitamin D deficiency was a significant risk factor for RHF (OR: 2.41; 95% CI, 1.72, 3.43; P < 0.001). Conclusions: Severe vitamin D deficiency is significantly associated with increasing prevalence of RHF in a relatively healthy adult population. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | American Society of Clinical Nutrition | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF CLINICAL NUTRITION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Severe vitamin D deficiency is a risk factor for renal hyperfiltration | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jong Hyun Jhee | - |
dc.contributor.googleauthor | Ki Heon Nam | - |
dc.contributor.googleauthor | Seong Yeong An | - |
dc.contributor.googleauthor | Min-Uk Cha | - |
dc.contributor.googleauthor | Misol Lee | - |
dc.contributor.googleauthor | Seohyun Park | - |
dc.contributor.googleauthor | Hyoungnae Kim | - |
dc.contributor.googleauthor | Hae-Ryong Yun | - |
dc.contributor.googleauthor | Youn Kyung Kee | - |
dc.contributor.googleauthor | Jung Tak Park | - |
dc.contributor.googleauthor | Seung Hyeok Han | - |
dc.contributor.googleauthor | Shin-Wook Kang | - |
dc.contributor.googleauthor | Tae-Hyun Yoo | - |
dc.identifier.doi | 10.1093/ajcn/nqy194 | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A00276 | - |
dc.contributor.localId | A01147 | - |
dc.contributor.localId | A01244 | - |
dc.contributor.localId | A01495 | - |
dc.contributor.localId | A01654 | - |
dc.contributor.localId | A02236 | - |
dc.contributor.localId | A02526 | - |
dc.contributor.localId | A04617 | - |
dc.contributor.localId | A02771 | - |
dc.contributor.localId | A05046 | - |
dc.contributor.localId | A04304 | - |
dc.relation.journalcode | J00074 | - |
dc.identifier.eissn | 1938-3207 | - |
dc.identifier.pmid | 30541088 | - |
dc.identifier.url | https://academic.oup.com/ajcn/article/108/6/1342/5239885 | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | 강신욱 | - |
dc.contributor.affiliatedAuthor | 기연경 | - |
dc.contributor.affiliatedAuthor | 김형래 | - |
dc.contributor.affiliatedAuthor | 남기헌 | - |
dc.contributor.affiliatedAuthor | 박서현 | - |
dc.contributor.affiliatedAuthor | 박정탁 | - |
dc.contributor.affiliatedAuthor | 안성영 | - |
dc.contributor.affiliatedAuthor | 유태현 | - |
dc.contributor.affiliatedAuthor | 윤해룡 | - |
dc.contributor.affiliatedAuthor | 이미솔 | - |
dc.contributor.affiliatedAuthor | 차민욱 | - |
dc.contributor.affiliatedAuthor | 한승혁 | - |
dc.citation.volume | 108 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1342 | - |
dc.citation.endPage | 1351 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF CLINICAL NUTRITION, Vol.108(6) : 1342-1351, 2018 | - |
dc.identifier.rimsid | 58068 | - |
dc.type.rims | ART | - |
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