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Temporal lobe epilepsy surgery in children versus adults: from etiologies to outcomes

DC Field Value Language
dc.contributor.author이준수-
dc.date.accessioned2019-01-18T16:40:13Z-
dc.date.available2019-01-18T16:40:13Z-
dc.date.issued2013-
dc.identifier.issn1738-1061-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/166904-
dc.description.abstractTemporal lobe epilepsy (TLE) is the most common type of medically intractable epilepsy in adults and children, and mesial temporal sclerosis is the most common underlying cause of TLE. Unlike in the case of adults, TLE in infants and young children often has etiologies other than mesial temporal sclerosis, such as tumors, cortical dysplasia, trauma, and vascular malformations. Differences in seizure semiology have also been reported. Motor manifestations are prominent in infants and young children, but they become less obvious with increasing age. Further, automatisms tend to become increasingly complex with age. However, in childhood and especially in adolescence, the clinical manifestations are similar to those of the adult population. Selective amygdalohippocampectomy can lead to excellent postoperative seizure outcome in adults, but favorable results have been seen in children as well. Anterior temporal lobectomy may prove to be a more successful surgery than amygdalohippocampectomy in children with intractable TLE. The presence of a focal brain lesion on magnetic resonance imaging is one of the most reliable independent predictors of a good postoperative seizure outcome. Seizure-free status is the most important predictor of improved psychosocial outcome with advanced quality of life and a lower proportion of disability among adults and children. Since the brain is more plastic during infancy and early childhood, recovery is promoted. In contrast, long epilepsy duration is an important risk factor for surgically refractory seizures. Therefore, patients with medically intractable TLE should undergo surgery as early as possible.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageKorean-
dc.publisher대한소아과학회-
dc.relation.isPartOfKorean Journal of Pediatrics-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleTemporal lobe epilepsy surgery in children versus adults: from etiologies to outcomes-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아청소년과학교실)-
dc.contributor.googleauthorYun-Jin Lee-
dc.contributor.googleauthorJoon Soo Lee-
dc.identifier.doi10.3345/kjp.2013.56.7.275-
dc.contributor.localIdA03177-
dc.relation.journalcodeJ02100-
dc.identifier.eissn2092-7258-
dc.identifier.pmid23908666-
dc.subject.keywordAdult-
dc.subject.keywordChild-
dc.subject.keywordTemporal lobe epilepsy-
dc.subject.keywordTemporal lobectomy-
dc.contributor.alternativeNameLee, Joon Soo-
dc.contributor.affiliatedAuthor이준수-
dc.citation.volume56-
dc.citation.number7-
dc.citation.startPage275-
dc.citation.endPage281-
dc.identifier.bibliographicCitationKorean Journal of Pediatrics, Vol.56(7) : 275-281, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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