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Environmental disinfection with photocatalyst as an adjunctive measure to control transmission of methicillin-resistant Staphylococcus aureus: a prospective cohort study in a high-incidence setting
DC Field | Value | Language |
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dc.contributor.author | 정수진 | - |
dc.date.accessioned | 2019-01-15T17:10:16Z | - |
dc.date.available | 2019-01-15T17:10:16Z | - |
dc.date.issued | 2018 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/166841 | - |
dc.description.abstract | BACKGROUND: Environmental disinfection with continuously antimicrobial surfaces could offer superior control of surface bioburden. We sought to decide the efficacy of photocatalyst antimicrobial coating in reducing methicillin-resistant Staphylococcus aureus (MRSA) acquisition in high incidence setting. METHODS: We performed prospective cohort study involving patients hospitalized in medical intensive care unit. A titanium dioxide-based photocatalyst was coated on high touch surfaces and walls. Five months of pre-intervention data were compared with five months of post-intervention data. The incidence rates of multidrug-resistant organism acquisition and the rates of hospital-acquired blood stream infection, pneumonia, urinary tract infection, and Clostridium difficile-associated diseases were compared using Cox proportional hazards regression analysis. RESULTS: In total, 621 patients were included. There was significant decrease in MRSA acquisition rate after photocatalyst coating (hazard ratio, 0.37; 95% confidence interval, 0.14-0.99; p = 0.04). However, clinical identification of vancomycin-resistant Enterococcus spp. and multidrug-resistant Acinetobacter baumannii did not decrease significantly. The hazard of contracting hospital-acquired pneumonia during the intervention period compared to baseline period was 0.46 (95% confidence interval, 0.23-0.94; p = 0.03). CONCLUSIONS: In conclusion, MRSA rate was significantly reduced after photocatalyst coating. We provide evidence that photocatalyst disinfection can be an adjunctive measure to control MRSA acquisition in high-incidence settings. TRIAL REGISTRATION: ISRCTN Registry ( ISRCTN31972004 ). Registered retrospectively on November 19, 2018. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | BioMed Central | - |
dc.relation.isPartOf | BMC INFECTIOUS DISEASES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Environmental disinfection with photocatalyst as an adjunctive measure to control transmission of methicillin-resistant Staphylococcus aureus: a prospective cohort study in a high-incidence setting | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Min Hyung Kim | - |
dc.contributor.googleauthor | Seong Gyu Lee | - |
dc.contributor.googleauthor | Ki Sook Kim | - |
dc.contributor.googleauthor | Yoon Ji Heo | - |
dc.contributor.googleauthor | Ji Eun Oh | - |
dc.contributor.googleauthor | Su Jin Jeong | - |
dc.identifier.doi | 10.1186/s12879-018-3555-1 | - |
dc.contributor.localId | A03638 | - |
dc.relation.journalcode | J00360 | - |
dc.identifier.eissn | 1471-2334 | - |
dc.identifier.pmid | 30509196 | - |
dc.subject.keyword | Environmental disinfection | - |
dc.subject.keyword | Hospital-acquired infection | - |
dc.subject.keyword | MRSA | - |
dc.subject.keyword | Photocatalyst | - |
dc.contributor.alternativeName | Jeong, Su Jin | - |
dc.contributor.affiliatedAuthor | 정수진 | - |
dc.citation.volume | 18 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 610 | - |
dc.identifier.bibliographicCitation | BMC INFECTIOUS DISEASES, Vol.18(1) : 610, 2018 | - |
dc.identifier.rimsid | 58213 | - |
dc.type.rims | ART | - |
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