Cited 2 times in
HBsAg-Negative, Anti-HBc-Negative Patients Still Have a Risk of Hepatitis B Virus-Related Hepatitis after Autologous Stem Cell Transplantation for Multiple Myeloma or Malignant Lymphoma
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김도영 | - |
dc.contributor.author | 김수정 | - |
dc.contributor.author | 김진석 | - |
dc.contributor.author | 민유홍 | - |
dc.contributor.author | 박현성 | - |
dc.contributor.author | 송재우 | - |
dc.contributor.author | 장지은 | - |
dc.contributor.author | 정준원 | - |
dc.contributor.author | 정해림 | - |
dc.contributor.author | 조현수 | - |
dc.date.accessioned | 2019-01-15T17:07:36Z | - |
dc.date.available | 2019-01-15T17:07:36Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1598-2998 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/166823 | - |
dc.description.abstract | PURPOSE: Although hepatitis B surface antigen (HBsAg)-negative, hepatitis B core antibody (anti-HBc)-negative patients are not considered to be at risk for hepatitis B virus (HBV)-related hepatitis, the actual risk remains to be elucidated. This study aimed to evaluate the risk of HBV-related hepatitis in HBsAg-negative, anti-HBc-negative patients receiving autologous stem cell transplantation (ASCT) for multiple myeloma (MM) or malignant lymphoma. Materials and Methods: We retrospectively reviewed data from 271 HBsAg-negative patients (161 anti-HBc-negative and 110 anti-HBc-positive at the time of ASCT) who received ASCT for MM or lymphoma. The risk of HBV-related hepatitis was analyzed according to the presence of anti-HBc. HBV serology results at the time of ASCT were compared with those at the time of diagnosis of MM or lymphoma. RESULTS: Three patients (two anti-HBc-negative MMs and one anti-HBc-positive MM) developed HBV-related hepatitis after ASCT. The rate of HBV-related hepatitis did not differ among patients with or without anti-HBc status (p=0.843). HBV-related hepatitis more frequently occurred in MM patients than in lymphoma patients (p=0.041). Overall, 9.1% of patients (16.7% with MM and 5.4% with lymphoma) who were HBsAg-negative and anti-HBc-positive at the time of diagnosis had lost anti-HBc positivity during chemotherapy prior to ASCT. CONCLUSION: Our data suggest that HBsAg-negative, anti-HBc-negative patients at the time of ASCT for MM or lymphoma still might be at a risk for HBV-related hepatitis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English, Korean | - |
dc.publisher | Official journal of Korean Cancer Association | - |
dc.relation.isPartOf | CANCER RESEARCH AND TREATMENT | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | HBsAg-Negative, Anti-HBc-Negative Patients Still Have a Risk of Hepatitis B Virus-Related Hepatitis after Autologous Stem Cell Transplantation for Multiple Myeloma or Malignant Lymphoma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Hyunsung Park | - |
dc.contributor.googleauthor | Do Young Kim | - |
dc.contributor.googleauthor | Soo-Jeong Kim | - |
dc.contributor.googleauthor | Haerim Chung | - |
dc.contributor.googleauthor | Hyunsoo Cho | - |
dc.contributor.googleauthor | Ji Eun Jang | - |
dc.contributor.googleauthor | June-Won Cheong | - |
dc.contributor.googleauthor | Yoo Hong Min | - |
dc.contributor.googleauthor | Jae-Woo Song | - |
dc.contributor.googleauthor | Jin Seok Kim | - |
dc.identifier.doi | 10.4143/crt.2017.329 | - |
dc.contributor.localId | A00385 | - |
dc.contributor.localId | A00633 | - |
dc.contributor.localId | A01017 | - |
dc.contributor.localId | A01407 | - |
dc.contributor.localId | A01740 | - |
dc.contributor.localId | A02054 | - |
dc.contributor.localId | A03477 | - |
dc.contributor.localId | A03729 | - |
dc.contributor.localId | A04674 | - |
dc.relation.journalcode | J00453 | - |
dc.identifier.eissn | 2005-9256 | - |
dc.identifier.pmid | 29198097 | - |
dc.subject.keyword | HBV-related hepatitis | - |
dc.subject.keyword | Hepatitis B core antibody | - |
dc.subject.keyword | Lymphoma | - |
dc.subject.keyword | Multiple myeloma | - |
dc.subject.keyword | Stem cell transplantation | - |
dc.contributor.alternativeName | Kim, Do Young | - |
dc.contributor.affiliatedAuthor | 김도영 | - |
dc.contributor.affiliatedAuthor | 김수정 | - |
dc.contributor.affiliatedAuthor | 김진석 | - |
dc.contributor.affiliatedAuthor | 민유홍 | - |
dc.contributor.affiliatedAuthor | 박현성 | - |
dc.contributor.affiliatedAuthor | 송재우 | - |
dc.contributor.affiliatedAuthor | 장지은 | - |
dc.contributor.affiliatedAuthor | 정준원 | - |
dc.contributor.affiliatedAuthor | 정해림 | - |
dc.citation.volume | 50 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1121 | - |
dc.citation.endPage | 1129 | - |
dc.identifier.bibliographicCitation | CANCER RESEARCH AND TREATMENT, Vol.50(4) : 1121-1129, 2018 | - |
dc.identifier.rimsid | 58198 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.