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Prognostic value of coronary computed tomographic angiography findings in asymptomatic individuals: a 6-year follow-up from the prospective multicentre international CONFIRM study
DC Field | Value | Language |
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dc.contributor.author | 장혁재 | - |
dc.date.accessioned | 2019-01-15T17:04:38Z | - |
dc.date.available | 2019-01-15T17:04:38Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0195-668X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/166789 | - |
dc.description.abstract | Aim: The long-term prognostic benefit of coronary computed tomographic angiography (CCTA) findings of coronary artery disease (CAD) in asymptomatic populations is unknown. Methods and results: From the prospective multicentre international CONFIRM long-term study, we evaluated asymptomatic subjects without known CAD who underwent both coronary artery calcium scoring (CACS) and CCTA (n = 1226). Coronary computed tomographic angiography findings included the severity of coronary artery stenosis, plaque composition, and coronary segment location. Using the C-statistic and likelihood ratio tests, we evaluated the incremental prognostic utility of CCTA findings over a base model that included a panel of traditional risk factors (RFs) as well as CACS to predict long-term all-cause mortality. During a mean follow-up of 5.9 ± 1.2 years, 78 deaths occurred. Compared with the traditional RF alone (C-statistic 0.64), CCTA findings including coronary stenosis severity, plaque composition, and coronary segment location demonstrated improved incremental prognostic utility beyond traditional RF alone (C-statistics range 0.71-0.73, all P < 0.05; incremental χ2 range 20.7-25.5, all P < 0.001). However, no added prognostic benefit was offered by CCTA findings when added to a base model containing both traditional RF and CACS (C-statistics P > 0.05, for all). Conclusions: Coronary computed tomographic angiography improved prognostication of 6-year all-cause mortality beyond a set of conventional RF alone, although, no further incremental value was offered by CCTA when CCTA findings were added to a model incorporating RF and CACS. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Oxford University Press | - |
dc.relation.isPartOf | EUROPEAN HEART JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Prognostic value of coronary computed tomographic angiography findings in asymptomatic individuals: a 6-year follow-up from the prospective multicentre international CONFIRM study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Iksung Cho | - |
dc.contributor.googleauthor | Subhi J Al’Aref | - |
dc.contributor.googleauthor | Adam Berger | - |
dc.contributor.googleauthor | Bríain Ó Hartaigh | - |
dc.contributor.googleauthor | Heidi Gransar | - |
dc.contributor.googleauthor | Valentina Valenti | - |
dc.contributor.googleauthor | Fay Y Lin | - |
dc.contributor.googleauthor | Stephan Achenbach | - |
dc.contributor.googleauthor | Daniel S Berman | - |
dc.contributor.googleauthor | Matthew J Budoff ... Show more | - |
dc.contributor.googleauthor | Tracy Q Callister | - |
dc.contributor.googleauthor | Mouaz H Al-Mallah | - |
dc.contributor.googleauthor | Filippo Cademartiri | - |
dc.contributor.googleauthor | Kavitha Chinnaiyan | - |
dc.contributor.googleauthor | Benjamin J W Chow | - |
dc.contributor.googleauthor | Augustin DeLago | - |
dc.contributor.googleauthor | Todd C Villines | - |
dc.contributor.googleauthor | Martin Hadamitzky | - |
dc.contributor.googleauthor | Joerg Hausleiter | - |
dc.contributor.googleauthor | Jonathon Leipsic | - |
dc.contributor.googleauthor | Leslee J Shaw | - |
dc.contributor.googleauthor | Philipp A Kaufmann | - |
dc.contributor.googleauthor | Gudrun Feuchtner | - |
dc.contributor.googleauthor | Yong-Jin Kim | - |
dc.contributor.googleauthor | Erica Maffei | - |
dc.contributor.googleauthor | Gilbert Raff | - |
dc.contributor.googleauthor | Gianluca Pontone | - |
dc.contributor.googleauthor | Daniele Andreini | - |
dc.contributor.googleauthor | Hugo Marques | - |
dc.contributor.googleauthor | Ronen Rubinshtein | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.contributor.googleauthor | James K Min | - |
dc.identifier.doi | 10.1093/eurheartj/ehx774 | - |
dc.contributor.localId | A03490 | - |
dc.relation.journalcode | J00805 | - |
dc.identifier.eissn | 1522-9645 | - |
dc.identifier.pmid | 29365193 | - |
dc.identifier.url | https://academic.oup.com/eurheartj/article/39/11/934/4815727 | - |
dc.subject.keyword | Coronary artery calcium scoring | - |
dc.subject.keyword | Coronary CT angiography | - |
dc.subject.keyword | Prognosis | - |
dc.subject.keyword | Coronary artery disease | - |
dc.subject.keyword | Computed tomography | - |
dc.subject.keyword | Atherosclerosis | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | 장혁재 | - |
dc.citation.volume | 39 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 934 | - |
dc.citation.endPage | 941 | - |
dc.identifier.bibliographicCitation | EUROPEAN HEART JOURNAL, Vol.39(11) : 934-941, 2018 | - |
dc.identifier.rimsid | 58056 | - |
dc.type.rims | ART | - |
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