Cited 18 times in
Clinical Benefit of Treatment of Stage-1, Low-Risk Hypertension : Korean National Health Insurance Database Analysis
DC Field | Value | Language |
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dc.contributor.author | 김현창 | - |
dc.contributor.author | 박성하 | - |
dc.date.accessioned | 2019-01-15T16:46:59Z | - |
dc.date.available | 2019-01-15T16:46:59Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0194-911X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/166636 | - |
dc.description.abstract | Evidence about the benefits of treating uncomplicated, low-risk, stage-1 hypertension is lacking. The study aimed to investigate the association between mean blood pressure (BP) and clinical outcomes, and to determine optimal BPs in treated, low-risk, stage-1 hypertension. From the National Health Insurance Service Health Examination Database, patients with stage-1 hypertension between 2005 and 2006 were selected. They had a systolic BP of 140 to 159 mm Hg or diastolic BP of 90 to 99 mm Hg. Patients were grouped as controlled (mean BP <140/90 mm Hg; n=99 301) and uncontrolled (mean BP ≥140/90 mm Hg; n=49 460) according to their mean BP recorded during the follow-up health examination. All-cause mortality and cardiovascular outcomes were examined. Mean BPs in the controlled and uncontrolled groups were 131.1/80.9 and 144.6/86.8 mm Hg, respectively. Controlled BP was associated with significantly lower risks of all-cause mortality, all stroke, hemorrhagic stroke, ischemic stroke, and end-stage renal disease. Subgroup analysis demonstrated benefits of controlled BP in hypertensive patients aged <50 years for all-cause mortality, all stroke, hemorrhagic stroke, ischemic stroke, and end-stage renal disease, with no significant interaction according to age. The BP associated with the lowest risk of all-cause mortality was 120 to <130 mm Hg (systolic BP) and 70 to <80 mm Hg (diastolic BP). There was an increased risk of myocardial infarction in patients with mean systolic BP <120 mm Hg and diastolic BP <80 mm Hg. BP <140/90 mm Hg was associated with a significant reduction in the risk of mortality, stroke, and end-stage renal disease, with the lowest mortality risk at BP ranges of 120 to <130 and 70 to <80 mm Hg. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott, Williams & Wilkins | - |
dc.relation.isPartOf | HYPERTENSION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Clinical Benefit of Treatment of Stage-1, Low-Risk Hypertension : Korean National Health Insurance Database Analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine and Public Health (예방의학교실) | - |
dc.contributor.googleauthor | Chan Joo Lee | - |
dc.contributor.googleauthor | Jiin Ryu | - |
dc.contributor.googleauthor | Hyeon-Chang Kim | - |
dc.contributor.googleauthor | Dong-Ryeol Ryu | - |
dc.contributor.googleauthor | Sang-Hyun Ihm | - |
dc.contributor.googleauthor | Yong-Jin Kim | - |
dc.contributor.googleauthor | Jin-Ho Shin | - |
dc.contributor.googleauthor | Wook Bum Pyun | - |
dc.contributor.googleauthor | Hyoung-Soo Kang | - |
dc.contributor.googleauthor | Jong-Heon Park | - |
dc.contributor.googleauthor | Jinseub Hwang | - |
dc.contributor.googleauthor | Sungha Park | - |
dc.identifier.doi | 10.1161/HYPERTENSIONAHA.118.11787 | - |
dc.contributor.localId | A01142 | - |
dc.contributor.localId | A01512 | - |
dc.relation.journalcode | J01015 | - |
dc.identifier.eissn | 1524-4563 | - |
dc.identifier.pmid | 30571236 | - |
dc.identifier.url | https://www.ahajournals.org/doi/full/10.1161/HYPERTENSIONAHA.118.11787 | - |
dc.subject.keyword | blood pressure | - |
dc.subject.keyword | hypertension | - |
dc.subject.keyword | mortality | - |
dc.subject.keyword | myocardial infarction | - |
dc.subject.keyword | stroke | - |
dc.contributor.alternativeName | Kim, Hyeon Chang | - |
dc.contributor.affiliatedAuthor | 김현창 | - |
dc.contributor.affiliatedAuthor | 박성하 | - |
dc.citation.volume | 72 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1285 | - |
dc.citation.endPage | 1293 | - |
dc.identifier.bibliographicCitation | HYPERTENSION, Vol.72(6) : 1285-1293, 2018 | - |
dc.identifier.rimsid | 57908 | - |
dc.type.rims | ART | - |
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