단일 지역사회 병원에서 관찰된 최근 5년간(2012~2016) 헤르페스 목구멍염으로 입원한 소아환자의 발생양상

Abstract

Purpose: Herpangina is one of the most frequent manifestations of enterovirus infection and sometimes it causes hospitalization due to complication. There are a few reports in Korea for the hospitalized cases after 2010, so I did this study to know its recent epidemiological features. Methods: I collected hospitalized herpangina patients who had been diagnosed and admitted at the Department of Pediatrics, Yongin Severance Hospital, Yongin, Korea from January 2012 to December 2016. I investigated their epidemiological and demographic data and analyzed them. Results: There were 143 cases of hospitalized herpangina for 5 years. The annual peak was found in 2013 (30.8%) and decreased from 2014 to 2016. Their monthly peak was found on June (40.2%) and one hundred and eleven cases (77.6%) were found from May to September. Monthly occurrence feature was bell-shaped in 2012 and 2013, but that was not observed from 2014 to 2015 and reappeared in 2016. Their total mean age was 1.7±2.1 years old. The most frequent age was 1 year old and one hundred and twenty-nine cases (90.2%) were found under 4 years old. Their annual mean ages were from 1.4±1.0 years old to 2.0±2.7 years old and there was no significant difference among them ( P =0.785). There were 73 boys and 70 girls. Male to female ratio was less than 1.0 until 2014 and reversed from 2015, but there was no significant statistical difference when comparing them year by year. Conclusion: It is still usually found under 4 years old and around July. But its cyclic occurrence has not happened and it has decreased continuously after 2013. There is no demographic difference by year since 2012. These epidemiological changes should be confirmed by further investigation.