소아 수족구병 입원 환자의 최근 임상양상: 지난 4년간(2009-2012) 용인지역

Abstract

Purpose: Hand, foot and mouth disease(HFMD) is a viral contagious disorder and it has been notorious for its neurological manifestations. There have been a few clinical studies for its general aspects in admitted children. The purpose of this investigation is to know their recent clinical features. Methods: I collected the patient informations of HFMD retrospectively who had been admitted and diagnosed clinically at the Department of Pediatrics, Yongin Severance Hospital, Yongin, Korea from January 2009 to December 2012. I investigated their clinical characteristics. Results: There were 32 cases for 4 years(20 boys and 12 girls). The mean age was 2.3 ± 0.4 years old. Twenty-three cases(71.9%) were younger than 3 years old. The peak month was July(37.5%). Initial clinical manifestations except oral ulcer and vesicular exanthem were poor oral intake(93.8%), fever(75.0%), sore throat(75.0%), cough(43.7%), rhinorrhea(40.6%), sputum(37.5%). There were 9 cases of pneumonia(28.1%), 3 bronchiolitis(9.4%), 3 gastroenteritis(9.4%), 2 sinusitis(6.3%). Serum aspartate transaminase , blood glucose and urinary leukocyte count level were elevated in 11 cases(34.4%), 8 cases(25.0%) and 16 cases(53.3%) respectively. Serum bicarbonate concentration was decreased in 18 cases(56.3%). Urinary ketone was found in 12 cases(40.0%). Duration of admission was 3.4 ± 1.4 days and only one patients were admitted more than 7 days. Conclusion: Although the prognosis of HFMD was favorable, the considerable proportion of the patients showed various systemic manifestations and organ involvements. Physicians should be cautioned for the possibility of its neurological involvements as well as other organ disorders. Continuous monitoring and study for it should be carried on for proper management and treatment.