361 499

Cited 34 times in

Design and Methods of the Korean Organ Transplantation Registry

DC Field Value Language
dc.contributor.author백효채-
dc.date.accessioned2018-12-18T16:40:06Z-
dc.date.available2018-12-18T16:40:06Z-
dc.date.issued2017-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/166168-
dc.description.abstractBACKGROUND: Beneficial aspects of solid organ transplantation, which encompass survival benefit, improved quality of life, and cost efficacy, have been clearly demonstrated. However, regional and ethnic differences require further studies to identify prognostic factors and transplant outcomes against various backgrounds. After previous efforts of a nationwide, retrospective study on the kidney transplant outcomes in Korea, a new prospective-designed version of the Korean Organ Transplantation Registry (KOTRY) was launched in 2014. METHODS: Cohorts of kidney, liver, heart, lung, and pancreas transplantation were developed. Data on demographics, comorbid conditions, laboratory tests, including tissue typing and panel reactive antibody tests, immunosuppressive regimen followed, concentration and dosage of immunosuppressants, allograft rejection type, infectious events, cardiovascular outcomes, malignancies, donor comorbidity, and outcomes of living donors are collected. Longitudinal data collection is based on a regular annual interval, and blood samples are collected before organ transplantation and again at 1 and 3 years posttransplantation. To enhance data quality, a predefined data verification system operates on a Web-based database, and transplant center users receive regular education about updates. Data are cleansed thrice a year, and feedback given to centers about outlier values and missing data. Annual auditing is conducted. RESULTS: Currently, 59 centers are participating in KOTRY. The estimated annual enrollment is more than 2000 cases. CONCLUSIONS: KOTRY, as a systematic Korean transplant cohort, is expected to provide important information on Asian organ transplantation. The processes used to establish KOTRY provide a good model for launching new nationwide transplant cohort studies.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherWolters Kluwer-
dc.relation.isPartOfTRANSPLANTATION DIRECT-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleDesign and Methods of the Korean Organ Transplantation Registry-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Thoracic and Cardiovascular Surgery (흉부외과학교실)-
dc.contributor.googleauthorJaeseok Yang-
dc.contributor.googleauthorJong Cheol Jeong-
dc.contributor.googleauthorJoongyub Lee-
dc.contributor.googleauthorYoung Hoon Kim-
dc.contributor.googleauthorHyo Chae Paik-
dc.contributor.googleauthorJae-Joong Kim-
dc.contributor.googleauthorHyun-young Park-
dc.contributor.googleauthorMyoung Soo Kim-
dc.contributor.googleauthorCurie Ahn-
dc.contributor.googleauthoron behalf of the KOTRY study group-
dc.identifier.doi10.1097/TXD.0000000000000678-
dc.contributor.localIdA01846-
dc.relation.journalcodeJ03551-
dc.identifier.eissn2373-8731-
dc.identifier.pmid28856244-
dc.contributor.alternativeNamePaik, Hyo Chae-
dc.contributor.affiliatedAuthor백효채-
dc.citation.volume3-
dc.citation.number8-
dc.citation.startPagee191-
dc.identifier.bibliographicCitationTRANSPLANTATION DIRECT, Vol.3(8) : e191, 2017-
dc.identifier.rimsid59290-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.