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ichroma SMART 장비의 C-reactive Protein과 Procalcitonin 분석능 평가

DC FieldValueLanguage
dc.contributor.author임정훈-
dc.date.accessioned2018-12-17T16:40:17Z-
dc.date.available2018-12-17T16:40:17Z-
dc.date.issued2016-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/166165-
dc.description.abstractBackground: For monitoring infection and inflammation episodes, biomarkers of host response, such as C-reactive protein (CRP) and procalcitonin (PCT), are now being recognized as useful tools in the diagnostic process. We aimed at evaluating the analytical performance of the recently developed semi-automated ichroma SMART system (Boditech Med Inc., Korea), which allows measurements of both CRP and PCT. Methods: We evaluated the analytical performance of the ichroma SMART system and the agreement between its results and the laboratory standards for CRP and PCT measurements. The precision and linearity as well as the method of measurement were compared to the DxC 800 (Beckman Coulter, USA) for CRP and to the VIDAS (bioMerieux SA, France) for PCT, according to corresponding CLSI guidelines. Additionally, we evaluated the carryover rates between specimens. Results: The total precision (% CV) of the ichroma SMART system in measuring low, middle, and high level controls (level 1, 2, 3) was 6.32%, 5.75%, and 3.56% for CRP, and 8.07%, 6.24%, and 6.53% for PCT. In the linearity test, R2 was 0.9997 and 0.9982 for CRP (0.1-336.8 mg/L) and PCT (0.05-60.91 ng/mL), respectively. Good correlation was observed between ichroma SMART and DxC 800 for CRP (r=0.997), and between ichroma SMART and VIDAS for PCT (r=0.992). Carry-over effect was 0.02% for CRP and 0.04% for PCT. Conclusions: The ichroma SMART system showed an adequate performance and appeared to be a suitable clinical analyzer with a simple operating procedure for the measurement of CRP and PCT.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageKorean-
dc.publisherKorean Society for Laboratory Medicine-
dc.relation.isPartOfLaboratory Medicine Online-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleichroma SMART 장비의 C-reactive Protein과 Procalcitonin 분석능 평가-
dc.title.alternativePerformance Evaluation of the ichroma SMART Analyzer in Measuring C-reactive Protein and Procalcitonin Levels-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pharmacology (약리학교실)-
dc.contributor.googleauthor임정훈-
dc.contributor.googleauthor안효준-
dc.contributor.googleauthor윤광국-
dc.contributor.googleauthor김혜련-
dc.contributor.googleauthor김영아-
dc.contributor.googleauthor임환섭-
dc.contributor.googleauthor유종하-
dc.contributor.localIdA04654-
dc.relation.journalcodeJ02151-
dc.identifier.eissn2093-6338-
dc.subject.keywordC-reactive protein-
dc.subject.keywordProcalcitonin-
dc.subject.keywordichroma SMART-
dc.contributor.alternativeNameRim, John Hoon-
dc.contributor.affiliatedAuthor임정훈-
dc.citation.volume6-
dc.citation.number1-
dc.citation.startPage19-
dc.citation.endPage24-
dc.identifier.bibliographicCitationLaboratory Medicine Online, Vol.6(1) : 19-24, 2016-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pharmacology (약리학교실) > 1. Journal Papers

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