Cited 2 times in
Natural history of mild aortic valve disease untreated at the time of rheumatic mitral valve replacement
DC Field | Value | Language |
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dc.contributor.author | 이삭 | - |
dc.contributor.author | 주현철 | - |
dc.contributor.author | 이승현 | - |
dc.contributor.author | 장병철 | - |
dc.date.accessioned | 2018-12-14T16:40:30Z | - |
dc.date.available | 2018-12-14T16:40:30Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1569-9293 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/166146 | - |
dc.description.abstract | OBJECTIVES: The aim of this study was to examine long-term clinical outcomes and to assess the eventual need for aortic valve replacement (AVR) in patients with mild aortic valve disease (AVD) at the time of mitral valve replacement. METHODS: Between 1990 and 2015, 1231 patients undergoing mitral valve replacement were reviewed, stratifying subjects as those with AVD (n = 363) or without AVD (NA; n = 868). Primary end points were progressive AVD (grade ≥ II) and subsequent AVR. Overall mortality and valve-related complications served as secondary end points. Propensity score matching was used for risk adjustment (n = 320 in each group). RESULTS: No differences in postoperative complications or clinical outcomes were observed between groups. The 20-year overall survival was similar (before matching: NA 86.1% vs AVD 80.8%, P = 0.128; after matching: 83.5% vs 81.1%, P = 0.425). Of the entire cohort, progressive AVD was observed in 162 patients, and significant AVD (grade ≥ III) was observed in only 60 patients. Subsequent AVR was required in 37 patients due to mitral valve (MV) dysfunction or severe aortic stenosis. The 20-year freedom from significant AVD and subsequent AVR was significantly higher in the NA group than in the AVD group before and after matching (before: NA, 96.5% vs 73.7%, P < 0.001; AVD, 98.5% vs 82.3%, P < 0.001; after: 98.1% vs 73.3%, P < 0.001; 99.3% vs 82.5%, P < 0.001, respectively). CONCLUSIONS: Although progressive AVD did not significantly impact long-term survival during the follow-up period, those patients qualifying initially as mild AVD may eventually progress to significant AVD after the first 5 postoperative years. Therefore, aggressive echocardiography should be performed at 5-year lapse after mitral valve replacement to determine the appropriate timing of AVR. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Oxford University Press | - |
dc.relation.isPartOf | INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Natural history of mild aortic valve disease untreated at the time of rheumatic mitral valve replacement | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) | - |
dc.contributor.googleauthor | Do Jung Kim | - |
dc.contributor.googleauthor | Hyun-Chel Joo | - |
dc.contributor.googleauthor | Seung-Hyun Lee | - |
dc.contributor.googleauthor | Byung-Chul Chang | - |
dc.contributor.googleauthor | Sak Lee | - |
dc.identifier.doi | 10.1093/icvts/ivy176 | - |
dc.contributor.localId | A02807 | - |
dc.contributor.localId | A03960 | - |
dc.contributor.localId | A02935 | - |
dc.contributor.localId | A03430 | - |
dc.relation.journalcode | J01070 | - |
dc.identifier.eissn | 1569-9285 | - |
dc.identifier.pmid | 29873732 | - |
dc.identifier.url | https://academic.oup.com/icvts/article-lookup/doi/10.1093/icvts/ivy176 | - |
dc.contributor.alternativeName | Lee, Sak | - |
dc.contributor.affiliatedAuthor | 이삭 | - |
dc.contributor.affiliatedAuthor | 주현철 | - |
dc.contributor.affiliatedAuthor | 이승현 | - |
dc.contributor.affiliatedAuthor | 장병철 | - |
dc.citation.volume | 27 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 828 | - |
dc.citation.endPage | 835 | - |
dc.identifier.bibliographicCitation | INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, Vol.27(6) : 828-835, 2018 | - |
dc.identifier.rimsid | 58312 | - |
dc.type.rims | ART | - |
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