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Temporal pole morphology and psychopathology in males with schizophrenia

DC FieldValueLanguage
dc.contributor.author김재진-
dc.date.accessioned2018-11-27T16:56:34Z-
dc.date.available2018-11-27T16:56:34Z-
dc.date.issued2004-
dc.identifier.issn0925-4927-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/165911-
dc.description.abstractA dysfunction of the paralimbic system has been implicated in the pathophysiology of schizophrenia. The temporal pole (TP) is a relevant component of the paralimbic circuit. Functional and structural imaging studies have shown circumscribed abnormalities in the TP. Subjects were 30 controls and 30 schizophrenia patients. Cortical surface size and gray matter volume of the TP were accurately measured to explore the morphology of the TP cortex and the relationship of TP measures to clinical variables in patients with schizophrenia. Correlations between structural measures and clinical dimensions, duration of illness, and cumulative neuroleptic exposure were determined. Neither macroscopic abnormalities in the TP nor differences in the pattern of asymmetry were demonstrated. The TP volume was correlated negatively to the psychotic and disorganized dimension scores. No other significant correlations were found. No morphological abnormalities in the TP were found in patients with schizophrenia. Interestingly, a reduction in the TP volume, a higher-order multimodal association cortex, was associated with the severity of disorganized and psychotic symptoms-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier/North-Holland Biomedical Press-
dc.relation.isPartOfPSYCHIATRY RESEARCH-NEUROIMAGING-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHDiagnostic and Statistical Manual of Mental Disorders-
dc.subject.MESHHumans-
dc.subject.MESHLimbic System/abnormalities-
dc.subject.MESHLimbic System/physiopathology-
dc.subject.MESHMagnetic Resonance Imaging-
dc.subject.MESHMale-
dc.subject.MESHReproducibility of Results-
dc.subject.MESHSchizophrenia/diagnosis-
dc.subject.MESHSchizophrenia/physiopathology*-
dc.subject.MESHSchizophrenic Psychology*-
dc.subject.MESHTemporal Lobe/abnormalities-
dc.subject.MESHTemporal Lobe/physiopathology*-
dc.titleTemporal pole morphology and psychopathology in males with schizophrenia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Psychiatry (정신과학교실)-
dc.contributor.googleauthorBenedicto Crespo-Facorroa-
dc.contributor.googleauthorPeggy C. Nopoulosa-
dc.contributor.googleauthorEran Chemerinskia-
dc.contributor.googleauthorJae-Jin Kim-
dc.contributor.googleauthorNancy C. Andreasena-
dc.contributor.googleauthorVincent Magnotta-
dc.identifier.doi10.1016/j.pscychresns.2004.09.002-
dc.contributor.localIdA00870-
dc.relation.journalcodeJ02570-
dc.identifier.eissn1872-7123-
dc.identifier.pmid15598545-
dc.contributor.alternativeNameKim, Jae Jin-
dc.contributor.affiliatedAuthor김재진-
dc.citation.volume132-
dc.citation.number2-
dc.citation.startPage107-
dc.citation.endPage115-
dc.identifier.bibliographicCitationPSYCHIATRY RESEARCH-NEUROIMAGING, Vol.132(2) : 107-115, 2004-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers

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