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단일 3차 의료 기관의 약물 유발 아나필락시스 발생 현황
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 문일주 | - |
dc.contributor.author | 박혜정 | - |
dc.contributor.author | 김성렬 | - |
dc.contributor.author | 고범석 | - |
dc.contributor.author | 임동우 | - |
dc.contributor.author | 박경희 | - |
dc.contributor.author | 이재현 | - |
dc.contributor.author | 박중원 | - |
dc.date.accessioned | 2018-11-26T05:55:16Z | - |
dc.date.available | 2018-11-26T05:55:16Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1738-9364 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/165821 | - |
dc.description.abstract | Background/Aims: Drug-induced anaphylaxis (DIA) is a severe, acute, and potentially life-threatening condition. In Korea, only a few well-documented cases of DIA have been described. Therefore, the aim of this study was to investigate the clinical characteristics, causes, and management of DIA in a single Korean medical institute. Methods: This was a retrospective medical record review of all DIA patients who visited the in-patient, out-patient, and emergency departments of our hospital from January 1 2006 to October 30 2013. Results: Among 605 cases of anaphylaxis, 167 were drug-induced. The culprit drugs were contrast agents (43 cases, 25.7%), antibiotics (38, 22.8%), non-steroidal anti-inflammatory drugs (35, 21.0%), anti-cancer drugs (22, 13.2%), parenteral vitamins (9, 5.4%), ranitidine (6, 3.6%), and neuromuscular blockers (3, 1.8%). The most common organ-specific symptoms/signs were cardiovascular (74.3%), cutaneous (71.3%), respiratory (55.7%), and gastrointestinal manifestations (19.2%). In most cases, DIA was treated with antihistamines (77.2%) and systemic corticosteroids (76.5%); the use of epinephrine was considerably less frequent (35.3%). Conclusions: In our institution, contrast agents were the leading cause of DIA. Although epinephrine is the drug of choice in the treatment of acute anaphylaxis, fewer than 50% of the study patients received epinephrine to treat DIA. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean | - |
dc.publisher | 대한내과학회 | - |
dc.relation.isPartOf | Korean Journal of Medicine | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 단일 3차 의료 기관의 약물 유발 아나필락시스 발생 현황 | - |
dc.title.alternative | Drug-Induced Anaphylaxis in a Single Korean Tertiary Hospital | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | 문일주 | - |
dc.contributor.googleauthor | 박혜정 | - |
dc.contributor.googleauthor | 김성렬 | - |
dc.contributor.googleauthor | 고범석 | - |
dc.contributor.googleauthor | 임동우 | - |
dc.contributor.googleauthor | 박경희 | - |
dc.contributor.googleauthor | 이재현 | - |
dc.contributor.googleauthor | 박중원 | - |
dc.identifier.doi | 10.3904/kjm.2015.88.3.281 | - |
dc.contributor.localId | A01375 | - |
dc.contributor.localId | A01769 | - |
dc.contributor.localId | A00566 | - |
dc.contributor.localId | A00119 | - |
dc.contributor.localId | A03360 | - |
dc.contributor.localId | A01427 | - |
dc.contributor.localId | A03086 | - |
dc.contributor.localId | A01681 | - |
dc.relation.journalcode | J02059 | - |
dc.subject.keyword | Anaphylaxis | - |
dc.subject.keyword | Epidemiology | - |
dc.subject.keyword | Epinephrine | - |
dc.subject.keyword | Adverse drug reaction | - |
dc.contributor.alternativeName | Moon, Il Joo | - |
dc.contributor.affiliatedAuthor | 문일주 | - |
dc.contributor.affiliatedAuthor | 박혜정 | - |
dc.contributor.affiliatedAuthor | 김성렬 | - |
dc.contributor.affiliatedAuthor | 고범석 | - |
dc.contributor.affiliatedAuthor | 임동우 | - |
dc.contributor.affiliatedAuthor | 박경희 | - |
dc.contributor.affiliatedAuthor | 이재현 | - |
dc.contributor.affiliatedAuthor | 박중원 | - |
dc.citation.volume | 88 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 281 | - |
dc.citation.endPage | 287 | - |
dc.identifier.bibliographicCitation | Korean Journal of Medicine, Vol.88(3) : 281-287, 2015 | - |
dc.identifier.rimsid | 60833 | - |
dc.type.rims | ART | - |
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