Cited 39 times in
Extranodal natural killer/T-cell lymphoma from skin or soft tissue: suggestion of treatment from multinational retrospective analysis.
DC Field | Value | Language |
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dc.contributor.author | 김진석 | - |
dc.date.accessioned | 2018-11-23T11:33:08Z | - |
dc.date.available | 2018-11-23T11:33:08Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0923-7534 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/165801 | - |
dc.description.abstract | BACKGROUND: Clinical features and outcomes of extranodal natural killer/T-cell lymphoma (ENKL) arising from extranasal sites are not fully understood. The purpose of this study was to study the prognosis and treatment outcome of skin/soft tissue primary ENKL. PATIENTS AND METHODS: This multicenter retrospective study included 48 patients with skin/soft tissue primary ENKL diagnosed from 1993 to 2010. RESULTS: Patients with Ann Arbor stage I, T1-2N0M0 by International Society for Cutaneous Lymphomas-European Organization of Research and Treatment of Cancer TNM (tumour-node-metastasis) stage, International prognostic index score of 0-1, and a Korean prognostic index (KPI) score of 0-1 were associated with better survival. Four of five patients with T1-2N0M0 disease achieved complete response with radiation alone. In disseminated disease, only 6 of 13 patients responded to anthracycline-containing chemotherapy, and all the two patients receiving SMILE showed response. CONCLUSION: In conclusion, we identified the prognostic value of KPI, and we suggest a treatment recommendation according to the TNM (tumour-node-metastasis) stage. Radiotherapy with/without chemotherapy seemed to be optimal in localized disease. In advanced stages, a more aggressive treatment regimen with newer agents should be sought. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Oxford University Press | - |
dc.relation.isPartOf | ANNALS OF ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Killer Cells, Natural/immunology* | - |
dc.subject.MESH | Lymphoma, T-Cell/immunology* | - |
dc.subject.MESH | Lymphoma, T-Cell/therapy | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Skin Neoplasms/immunology* | - |
dc.subject.MESH | Skin Neoplasms/therapy | - |
dc.subject.MESH | Soft Tissue Neoplasms/immunology* | - |
dc.subject.MESH | Soft Tissue Neoplasms/therapy | - |
dc.subject.MESH | Young Adult | - |
dc.title | Extranodal natural killer/T-cell lymphoma from skin or soft tissue: suggestion of treatment from multinational retrospective analysis. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | H. K. Ahn | - |
dc.contributor.googleauthor | C. Suh | - |
dc.contributor.googleauthor | S. S. Chuang | - |
dc.contributor.googleauthor | J. Suzumiya | - |
dc.contributor.googleauthor | Y. H. Ko | - |
dc.contributor.googleauthor | S. J. Kim | - |
dc.contributor.googleauthor | J. R. Huh | - |
dc.contributor.googleauthor | D. H. Yoon | - |
dc.contributor.googleauthor | S. Y. Oh | - |
dc.contributor.googleauthor | J. S. Kim | - |
dc.contributor.googleauthor | S. I. Lee | - |
dc.contributor.googleauthor | K. W. Park | - |
dc.contributor.googleauthor | P. P. Hsieh | - |
dc.contributor.googleauthor | S. Nakamura | - |
dc.contributor.googleauthor | T. Yoshino | - |
dc.contributor.googleauthor | K. Ito | - |
dc.contributor.googleauthor | T. Nagatani | - |
dc.contributor.googleauthor | K. Oshimi | - |
dc.contributor.googleauthor | R. Suzuki | - |
dc.contributor.googleauthor | W. S. Kim | - |
dc.identifier.doi | 10.1093/annonc/mds096 | - |
dc.contributor.localId | A01017 | - |
dc.relation.journalcode | J00171 | - |
dc.identifier.eissn | 1569-8041 | - |
dc.identifier.pmid | 22547542 | - |
dc.identifier.url | https://academic.oup.com/annonc/article/23/10/2703/194068 | - |
dc.subject.keyword | chemotherapy | - |
dc.subject.keyword | extranodal NK/T-cell lymphoma | - |
dc.subject.keyword | prognosis | - |
dc.subject.keyword | skin | - |
dc.subject.keyword | radiation therapy | - |
dc.contributor.alternativeName | Kim, Jin Seok | - |
dc.contributor.affiliatedAuthor | 김진석 | - |
dc.citation.volume | 23 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 2703 | - |
dc.citation.endPage | 2707 | - |
dc.identifier.bibliographicCitation | ANNALS OF ONCOLOGY, Vol.23(10) : 2703-2707, 2012 | - |
dc.identifier.rimsid | 60542 | - |
dc.type.rims | ART | - |
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