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Local excision after neoadjuvant chemoradiation therapy in advanced rectal cancer: a national multicenter analysis

DC FieldValueLanguage
dc.contributor.author김남규-
dc.date.accessioned2018-11-19T16:41:44Z-
dc.date.available2018-11-19T16:41:44Z-
dc.date.issued2013-
dc.identifier.issn0002-9610-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/165599-
dc.description.abstractBACKGROUND: The aim of the current study was to evaluate the clinical availability of local excision (LE) for advanced rectal cancer without lymph node metastasis after neoadjuvant chemoradiation therapy (nCRT) in Korea. METHODS: From June 2000 to October 2009, 40 patients with cT2-3N0M0 rectal cancer underwent nCRT followed by LE according to a retrospective multicenter analysis. RESULTS: Of the 40 patients, 22 were men and 18 were women. Eighteen patients were cT2, and 22 patients were cT3. The median follow-up duration was 38 months. Three patients (7.5%) had morbidity after LE. Four patients (10%) had recurrence (local recurrence [1 patient] and systemic metastasis [3 patients]). The 3-year disease-free survival rate was 85.9%. Only pCR was a recurrence-related prognostic factor (P = .040). CONCLUSIONS: Although the current study was not a randomized controlled study, LE after nCRT in T2-3N0 rectal cancer patients appears to be a safe and effective treatment, especially in pCR patients.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherExcerpta Medica-
dc.relation.isPartOfAMERICAN JOURNAL OF SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHChemoradiotherapy*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoadjuvant Therapy*-
dc.subject.MESHNeoplasm Metastasis-
dc.subject.MESHNeoplasm Recurrence, Local-
dc.subject.MESHRectal Neoplasms/mortality-
dc.subject.MESHRectal Neoplasms/pathology-
dc.subject.MESHRectal Neoplasms/therapy*-
dc.subject.MESHRectum/surgery*-
dc.subject.MESHRetrospective Studies-
dc.titleLocal excision after neoadjuvant chemoradiation therapy in advanced rectal cancer: a national multicenter analysis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학교실)-
dc.contributor.googleauthorChang Sik Yu-
dc.contributor.googleauthorHae Ran Yun-
dc.contributor.googleauthorEung Jin Shin-
dc.contributor.googleauthorKang Yong Lee-
dc.contributor.googleauthorNam Kyu Kim-
dc.contributor.googleauthorSeok-Byung Lim-
dc.contributor.googleauthorSeong Taek Oh-
dc.contributor.googleauthorSung-Bum Kang-
dc.contributor.googleauthorWon Joon Choi-
dc.contributor.googleauthorWoo Yong Lee-
dc.identifier.doi10.1016/j.amjsurg.2013.01.042-
dc.contributor.localIdA00353-
dc.contributor.localIdA00353-
dc.relation.journalcodeJ00119-
dc.identifier.eissn1879-1883-
dc.identifier.pmid23849272-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0002961013002948-
dc.subject.keywordLocal excision-
dc.subject.keywordNeoadjuvant chemoradiation therapy-
dc.subject.keywordRectal cancer-
dc.contributor.alternativeNameKim, Nam Kyu-
dc.contributor.affiliatedAuthor김남규-
dc.citation.volume206-
dc.citation.number4-
dc.citation.startPage482-
dc.citation.endPage487-
dc.identifier.bibliographicCitationAMERICAN JOURNAL OF SURGERY, Vol.206(4) : 482-487, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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