Cited 17 times in
Efficacy of hemostatic powder in preventing bleeding after gastric endoscopic submucosal dissection in high-risk patients.
DC Field | Value | Language |
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dc.contributor.author | 박준철 | - |
dc.contributor.author | 신성관 | - |
dc.contributor.author | 이상길 | - |
dc.contributor.author | 이용강 | - |
dc.contributor.author | 이용찬 | - |
dc.date.accessioned | 2018-11-16T16:59:40Z | - |
dc.date.available | 2018-11-16T16:59:40Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0815-9319 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/165556 | - |
dc.description.abstract | BACKGROUND AND AIM: The prevention of post-endoscopic submucosal dissection (ESD) bleeding in high-risk patients is an important problem. This study evaluated the efficacy of polysaccharide hemostatic powder in preventing post-ESD bleeding in high-risk patients. METHODS: Patients at high risk for post-ESD bleeding were prospectively enrolled between December 2015 and July 2016. A high risk of post-ESD bleeding was considered if the patients were taking antithrombotic agents or had undergone a large resection (specimen size ≥ 40 mm). The endpoints were Forrest classification of the post-ESD ulcer on second-look endoscopy 2 days after the procedure and bleeding rates within 48 h and at 4 weeks. RESULTS: Forty-four patients underwent gastric ESD and treatment with hemostatic powder. Among them, 33 patients (70.5%) underwent large resection (≥ 40 mm) without antithrombotic therapy, and 13 patients (29.5%) received antithrombotic therapy. The mean resected specimen size was 55.3 ± 13.9 mm. The proportion of high-risk delayed bleeding lesions (Forrest IIa) at second-look endoscopy was 4.5% (2/44). The overall bleeding rate was 9.1% (4/44). There was no early bleeding event. The median (interquartile range) timing of bleeding after the procedure was 12.5 (interquartile range 10.3-15.5) days. The bleeding rate in the large resection (≥ 40 mm) group without antithrombotic therapy and the antithrombotic therapy group was 3.2% (1/33) and 23.1% (3/13), respectively. CONCLUSIONS: Hemostatic powder may be a promising new simple and effective method to prevent early post-ESD bleeding in high-risk patients, especially for those with larger resection. (Clinical trial registration number: NCT02625792). | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Blackwell Scientific Publications | - |
dc.relation.isPartOf | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Blood Loss, Surgical/prevention & control* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fibrinolytic Agents/adverse effects | - |
dc.subject.MESH | Gastric Mucosa/surgery* | - |
dc.subject.MESH | Gastrointestinal Hemorrhage/etiology | - |
dc.subject.MESH | Gastrointestinal Hemorrhage/prevention & control* | - |
dc.subject.MESH | Gastroscopy* | - |
dc.subject.MESH | Hemostasis, Surgical/methods* | - |
dc.subject.MESH | Hemostatics/administration & dosage* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Polysaccharides/administration & dosage* | - |
dc.subject.MESH | Postoperative Complications/etiology | - |
dc.subject.MESH | Postoperative Complications/prevention & control* | - |
dc.subject.MESH | Powders | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Risk | - |
dc.subject.MESH | Second-Look Surgery | - |
dc.subject.MESH | Time Factors | - |
dc.title | Efficacy of hemostatic powder in preventing bleeding after gastric endoscopic submucosal dissection in high-risk patients. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Kyu Yeon Hahn | - |
dc.contributor.googleauthor | Jun Chul Park | - |
dc.contributor.googleauthor | Yong Kang Lee | - |
dc.contributor.googleauthor | Sung Kwan Shin | - |
dc.contributor.googleauthor | Sang Kil Lee | - |
dc.contributor.googleauthor | Yong Chan Lee | - |
dc.identifier.doi | 10.1111/jgh.13990 | - |
dc.contributor.localId | A01676 | - |
dc.contributor.localId | A02112 | - |
dc.contributor.localId | A02812 | - |
dc.contributor.localId | A02973 | - |
dc.contributor.localId | A02988 | - |
dc.relation.journalcode | J01417 | - |
dc.identifier.eissn | 1440-1746 | - |
dc.identifier.pmid | 28910851 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/full/10.1111/jgh.13990 | - |
dc.subject.keyword | adverse event | - |
dc.subject.keyword | antithrombotic therapy | - |
dc.subject.keyword | endoscopic submucosal dissection | - |
dc.subject.keyword | hemostatic powder | - |
dc.subject.keyword | high risk of bleeding | - |
dc.subject.keyword | post-ESD bleeding | - |
dc.contributor.alternativeName | Park, Jun Chul | - |
dc.contributor.alternativeName | Shin, Sung Kwan | - |
dc.contributor.alternativeName | Lee, Sang Kil | - |
dc.contributor.alternativeName | Lee, Yong Kang | - |
dc.contributor.alternativeName | Lee, Yong Chan | - |
dc.contributor.affiliatedAuthor | 박준철 | - |
dc.contributor.affiliatedAuthor | 신성관 | - |
dc.contributor.affiliatedAuthor | 이상길 | - |
dc.contributor.affiliatedAuthor | 이용강 | - |
dc.contributor.affiliatedAuthor | 이용찬 | - |
dc.citation.volume | 33 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 656 | - |
dc.citation.endPage | 663 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Vol.33(3) : 656-663, 2018 | - |
dc.identifier.rimsid | 59190 | - |
dc.type.rims | ART | - |
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