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Impact of peripheral artery disease on early and late outcomes of transcatheter aortic valve implantation in patients with severe aortic valve stenosis

DC Field Value Language
dc.contributor.author고영국-
dc.contributor.author김병규-
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author안철민-
dc.contributor.author이삭-
dc.contributor.author이승현-
dc.contributor.author장병철-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.contributor.author홍성진-
dc.date.accessioned2018-11-16T16:56:38Z-
dc.date.available2018-11-16T16:56:38Z-
dc.date.issued2018-
dc.identifier.issn0167-5273-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/165499-
dc.description.abstractAIMS: Peripheral artery disease (PAD) is frequently present in patients undergoing transcatheter aortic valve implantation (TAVI) for severe aortic stenosis. This study assessed the impact of PAD on clinical outcome after TAVI. METHODS: A total of 115 patients who underwent TAVI were evaluated retrospectively. Patients were divided into PAD and non-PAD groups, with PAD defined as stenosis≥50% in lower extremity arteries. Immediate and late clinical outcomes were compared between the two groups. RESULTS: PAD was present in 31.3% (36/115) of the patients undergoing TAVI. Compared to the non-PAD group, the PAD group had higher Society of Thoracic Surgeons' (STS) risk scores (8.83%±6.20% vs 6.23%±4.15%, p=0.039) and more frequent diagnoses of diabetes (52.8% vs 30.4%, p=0.021) and multi-vessel coronary artery disease (55.6% vs 29.1%, p=0.007). The PAD group also had higher incidence of major vascular complication (11.1% vs 1.3%, p=0.033), 30-day mortality (13.9% vs 1.3%, p<0.001), and subsequent 1-year (30.6% vs 3.8%, p<0.001) and 2-year (47.2% vs. 10.1%, p<0.001) all-cause mortality. PAD was identified as an independent predictor of increased 1-year mortality (hazard ratio [HR] 8.65; 95% confidence interval [CI], 1.05-71.14, p=0.045) after TAVI along with high STS score (HR 11.18, 95% CI 1.36-92.04, p=0.025). CONCLUSIONS: Presence of PAD was significantly associated with increased rates of major vascular complications as well as immediate and late mortality in patients undergoing TAVI. Assessment of PAD before TAVI is essential to choose an access strategy and to predict clinical results.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAortic Valve Stenosis/diagnostic imaging*-
dc.subject.MESHAortic Valve Stenosis/mortality-
dc.subject.MESHAortic Valve Stenosis/surgery*-
dc.subject.MESHComputed Tomography Angiography/mortality-
dc.subject.MESHComputed Tomography Angiography/trends-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMortality/trends-
dc.subject.MESHPeripheral Arterial Disease/diagnostic imaging*-
dc.subject.MESHPeripheral Arterial Disease/mortality-
dc.subject.MESHPeripheral Arterial Disease/surgery*-
dc.subject.MESHPostoperative Complications/diagnostic imaging-
dc.subject.MESHPostoperative Complications/mortality-
dc.subject.MESHRegistries-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHSeverity of Illness Index*-
dc.subject.MESHTranscatheter Aortic Valve Replacement/adverse effects-
dc.subject.MESHTranscatheter Aortic Valve Replacement/mortality-
dc.subject.MESHTranscatheter Aortic Valve Replacement/trends*-
dc.subject.MESHTreatment Outcome-
dc.titleImpact of peripheral artery disease on early and late outcomes of transcatheter aortic valve implantation in patients with severe aortic valve stenosis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorByung Gyu Kim-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorSung-Jin Hong-
dc.contributor.googleauthorChul-Min Ahn-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.contributor.googleauthorSeung Hyun Lee-
dc.contributor.googleauthorSak Lee-
dc.contributor.googleauthorByung-Chul Chang-
dc.identifier.doi10.1016/j.ijcard.2017.11.065-
dc.contributor.localIdA00127-
dc.contributor.localIdA05586-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA02269-
dc.contributor.localIdA02807-
dc.contributor.localIdA02935-
dc.contributor.localIdA03430-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.contributor.localIdA04403-
dc.relation.journalcodeJ01093-
dc.identifier.eissn1874-1754-
dc.identifier.pmid29425561-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0167527317337154-
dc.subject.keywordAortic stenosis-
dc.subject.keywordClinical outcome-
dc.subject.keywordPeripheral artery disease-
dc.subject.keywordTranscatheter aortic valve implantation-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameKim, Byung Gyu-
dc.contributor.alternativeNameKim, Byeong Keuk-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameAhn, Chul Min-
dc.contributor.alternativeNameLee, Sak-
dc.contributor.alternativeNameLee, Seung Hyun-
dc.contributor.alternativeNameChang, Byung Chul-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameHong, Myeong Ki-
dc.contributor.alternativeNameHong, Sung Jin-
dc.contributor.affiliatedAuthor고영국-
dc.contributor.affiliatedAuthor김병규-
dc.contributor.affiliatedAuthor김병극-
dc.contributor.affiliatedAuthor김중선-
dc.contributor.affiliatedAuthor안철민-
dc.contributor.affiliatedAuthor이삭-
dc.contributor.affiliatedAuthor이승현-
dc.contributor.affiliatedAuthor장병철-
dc.contributor.affiliatedAuthor장양수-
dc.contributor.affiliatedAuthor최동훈-
dc.contributor.affiliatedAuthor홍명기-
dc.contributor.affiliatedAuthor홍성진-
dc.citation.volume255-
dc.citation.startPage206-
dc.citation.endPage211-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF CARDIOLOGY, Vol.255 : 206-211, 2018-
dc.identifier.rimsid59110-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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