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Assessment of human placenta as an ex-vivo vascular model for testing of liquid embolic agent injections with adjunctive techniques.
DC Field | Value | Language |
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dc.contributor.author | 정준호 | - |
dc.date.accessioned | 2018-11-16T16:55:37Z | - |
dc.date.available | 2018-11-16T16:55:37Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1759-8478 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/165482 | - |
dc.description.abstract | PURPOSE: This project sought to test the utility of post-delivery human placenta (HP) as a vascular model for liquid embolic agent (LEA) simulation, along with adjunctive techniques. MATERIALS AND METHODS: Twelve LEA injections were performed under fluoroscopy in HP with two reflux control methods: dual lumen 'mini' balloon-catheter (n=9); and injection after proximal nBCA plug formation through a second microcatheter ('pressure cooker') (n=3). Measured outcomes included liquid embolic agent (LEA) advancement and reflux. Reflux was categorized into three grades: grade 0=no reflux; grade 1=occlusion of side branches without reflux beyond the balloon or plug; and grade 2=reflux beyond the balloon or plug. RESULTS: Simulation success was greater when a balloon was used rather than with a nBCA plug (89% vs 33%, P=0.054). In eight successful balloon-assisted injections, the reflux grades were: 50% grade 0; 12.5% grade 1; and 37.5% grade 2. The one successful nBCA plug injection had grade 2 reflux. All grade 2 balloon injections occurred when the balloon was positioned across a vessel bifurcation. CONCLUSIONS: HP provides excellent simulation for liquid embolic agents with a dual lumen balloon catheter. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | BMJ Publishing Group | - |
dc.relation.isPartOf | JOURNAL OF NEUROINTERVENTIONAL SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Balloon Embolectomy/methods* | - |
dc.subject.MESH | Dimethyl Sulfoxide/administration & dosage* | - |
dc.subject.MESH | Embolization, Therapeutic/methods* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluoroscopy/methods | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Injections | - |
dc.subject.MESH | Placenta/blood supply | - |
dc.subject.MESH | Placenta/diagnostic imaging* | - |
dc.subject.MESH | Placenta/drug effects* | - |
dc.subject.MESH | Polyvinyls/administration & dosage* | - |
dc.subject.MESH | Pregnancy | - |
dc.title | Assessment of human placenta as an ex-vivo vascular model for testing of liquid embolic agent injections with adjunctive techniques. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurosurgery (신경외과학교실) | - |
dc.contributor.googleauthor | Hideo Okada | - |
dc.contributor.googleauthor | Joonho Chung | - |
dc.contributor.googleauthor | Daniel M Heiferman | - |
dc.contributor.googleauthor | Demetrius K Lopes | - |
dc.identifier.doi | 10.1136/neurintsurg-2017-013474 | - |
dc.contributor.localId | A03731 | - |
dc.relation.journalcode | J02880 | - |
dc.identifier.eissn | 1759-8486 | - |
dc.identifier.pmid | 29273647 | - |
dc.identifier.url | https://jnis.bmj.com/content/10/9/892.long | - |
dc.subject.keyword | balloon | - |
dc.subject.keyword | liquid embolic material | - |
dc.subject.keyword | technique | - |
dc.contributor.alternativeName | Chung, Joon Ho | - |
dc.contributor.affiliatedAuthor | 정준호 | - |
dc.citation.volume | 10 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 892 | - |
dc.citation.endPage | 895 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NEUROINTERVENTIONAL SURGERY, Vol.10(9) : 892-895, 2018 | - |
dc.identifier.rimsid | 59093 | - |
dc.type.rims | ART | - |
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