0 53

Cited 0 times in

Assessment of human placenta as an ex-vivo vascular model for testing of liquid embolic agent injections with adjunctive techniques.

DC FieldValueLanguage
dc.contributor.author정준호-
dc.date.accessioned2018-11-16T16:55:37Z-
dc.date.available2018-11-16T16:55:37Z-
dc.date.issued2018-
dc.identifier.issn1759-8478-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/165482-
dc.description.abstractPURPOSE: This project sought to test the utility of post-delivery human placenta (HP) as a vascular model for liquid embolic agent (LEA) simulation, along with adjunctive techniques. MATERIALS AND METHODS: Twelve LEA injections were performed under fluoroscopy in HP with two reflux control methods: dual lumen 'mini' balloon-catheter (n=9); and injection after proximal nBCA plug formation through a second microcatheter ('pressure cooker') (n=3). Measured outcomes included liquid embolic agent (LEA) advancement and reflux. Reflux was categorized into three grades: grade 0=no reflux; grade 1=occlusion of side branches without reflux beyond the balloon or plug; and grade 2=reflux beyond the balloon or plug. RESULTS: Simulation success was greater when a balloon was used rather than with a nBCA plug (89% vs 33%, P=0.054). In eight successful balloon-assisted injections, the reflux grades were: 50% grade 0; 12.5% grade 1; and 37.5% grade 2. The one successful nBCA plug injection had grade 2 reflux. All grade 2 balloon injections occurred when the balloon was positioned across a vessel bifurcation. CONCLUSIONS: HP provides excellent simulation for liquid embolic agents with a dual lumen balloon catheter.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherBMJ Publishing Group-
dc.relation.isPartOfJournal of Neurointerventional Surgery-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBalloon Embolectomy/methods*-
dc.subject.MESHDimethyl Sulfoxide/administration & dosage*-
dc.subject.MESHEmbolization, Therapeutic/methods*-
dc.subject.MESHFemale-
dc.subject.MESHFluoroscopy/methods-
dc.subject.MESHHumans-
dc.subject.MESHInjections-
dc.subject.MESHPlacenta/blood supply-
dc.subject.MESHPlacenta/diagnostic imaging*-
dc.subject.MESHPlacenta/drug effects*-
dc.subject.MESHPolyvinyls/administration & dosage*-
dc.subject.MESHPregnancy-
dc.titleAssessment of human placenta as an ex-vivo vascular model for testing of liquid embolic agent injections with adjunctive techniques.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurosurgery (신경외과학교실)-
dc.contributor.googleauthorHideo Okada-
dc.contributor.googleauthorJoonho Chung-
dc.contributor.googleauthorDaniel M Heiferman-
dc.contributor.googleauthorDemetrius K Lopes-
dc.identifier.doi10.1136/neurintsurg-2017-013474-
dc.contributor.localIdA03731-
dc.contributor.localIdA03731-
dc.relation.journalcodeJ02880-
dc.identifier.eissn1759-8486-
dc.identifier.pmid29273647-
dc.identifier.urlhttps://jnis.bmj.com/content/10/9/892.long-
dc.subject.keywordballoon-
dc.subject.keywordliquid embolic material-
dc.subject.keywordtechnique-
dc.contributor.alternativeNameChung, Joon Ho-
dc.contributor.affiliatedAuthor정준호-
dc.citation.volume10-
dc.citation.number9-
dc.citation.startPage892-
dc.citation.endPage895-
dc.identifier.bibliographicCitationJournal of Neurointerventional Surgery, Vol.10(9) : 892-895, 2018-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.