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Total IgG의 신속한 반정량 검사키트 ImmuneCheck™ IgG의 임상적 유용성
DC Field | Value | Language |
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dc.contributor.author | 김현숙 | - |
dc.contributor.author | 박경희 | - |
dc.contributor.author | 박중원 | - |
dc.contributor.author | 이상철 | - |
dc.date.accessioned | 2018-11-16T16:44:35Z | - |
dc.date.available | 2018-11-16T16:44:35Z | - |
dc.date.issued | 2018 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/165282 | - |
dc.description.abstract | Background: Conventional IgG assays require costly equipment and skilled experts. Semiquantitative measurement of total IgG using point-of-care testing devices may be the solution for these limitations. This study evaluated the reproducibility of the ImmuneCheck™ IgG assay (ProteomeTech Inc., Korea) and the correlation of its results with conventional laboratory IgG results in the serum and whole blood. Methods: Both the serum and whole blood samples from 120 patients were used. To evaluate the intra-test reproducibility and inter-test correlation, intraclass correlation coefficient (ICC) analysis was used. Results: The concentration of serum total IgG measured by cobas® 6000 (Roche Diagnostics, Switzland) ranged from 690.4 to 2,756.4 mg/dL. The intra-test reproducibility of ImmuneCheck™ IgG was high (Serum ICC=0.724, P<0.001; Whole blood ICC=0.843, P<0.001). The inter-test correlation between the ImmuneCheck™ IgG and cobas® 6000 results was very good (Serum ICC=0.805, P<0.001; Whole blood ICC=0.842, P<0.001). Because there were no samples with a total IgG level lower than 600 mg/dL, the pre-existing serum samples were diluted and then the linearity tests were conducted. The intra-test reproducibility for the diluted serum samples was almost perfect (ICC=0.995, P<0.001), and the inter-test correlation between the ImmuneCheck™ IgG and cobas® 6000 results was also strong (ICC=0.992, P<0.001). Conclusions: The ImmuneCheck™ IgG assay is reproducible and highly correlated with the conventional IgG assay for the serum and whole blood. It could be applied for the rapid detection of total IgG | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean | - |
dc.publisher | Korean Society for Laboratory Medicine | - |
dc.relation.isPartOf | Laboratory Medicine Online | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Total IgG의 신속한 반정량 검사키트 ImmuneCheck™ IgG의 임상적 유용성 | - |
dc.title.alternative | Clinical Usefulness of ImmuneCheck™ IgG for Rapid Semiquantitation of Total IgG | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | 최진영 | - |
dc.contributor.googleauthor | 이상철 | - |
dc.contributor.googleauthor | 박경희 | - |
dc.contributor.googleauthor | 윤혜령 | - |
dc.contributor.googleauthor | 김현숙 | - |
dc.contributor.googleauthor | 박중원 | - |
dc.identifier.doi | 10.3343/lmo.2018.8.4.140 | - |
dc.contributor.localId | A01117 | - |
dc.contributor.localId | A01427 | - |
dc.contributor.localId | A01681 | - |
dc.contributor.localId | A02831 | - |
dc.relation.journalcode | J02151 | - |
dc.identifier.eissn | 2093-6338 | - |
dc.subject.keyword | Total IgG POCT | - |
dc.subject.keyword | Rapid semiquantitation | - |
dc.subject.keyword | Total IgG assay | - |
dc.contributor.alternativeName | Kim, Hyon Suk | - |
dc.contributor.alternativeName | Park, Kyung Hee | - |
dc.contributor.alternativeName | Park, Jung Won | - |
dc.contributor.alternativeName | Lee, Sang Chul | - |
dc.contributor.affiliatedAuthor | 김현숙 | - |
dc.contributor.affiliatedAuthor | 박경희 | - |
dc.contributor.affiliatedAuthor | 박중원 | - |
dc.contributor.affiliatedAuthor | 이상철 | - |
dc.citation.volume | 8 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 140 | - |
dc.citation.endPage | 147 | - |
dc.identifier.bibliographicCitation | Laboratory Medicine Online, Vol.8(4) : 140-147, 2018 | - |
dc.identifier.rimsid | 58696 | - |
dc.type.rims | ART | - |
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