Sarcoidosis is a multi-systemic granulomatous disease of unknown
cause, which most commonly involves lung, skin,
eye, liver and lymph nodes. Herein, we report a case of sarcoidosis
presented with massive ascites. A 47-year-old male
patient visited our hospital with symptoms of general weakness
and weight loss from past 4 months. Abdomen computed
tomography showed multiple lymphadenopathy and
hepatosplenomegaly. Lymph node biopsy demonstrated
non-caseating granulomas. After biopsy, development of
massive uncontrolled ascites was noted. Liver biopsy
showed non-cirrhotic hepatic and portal fibrosis and omental
biopsy showed submesothelial diffuse fibrosis and focal
chronic inflammation, which were suggestive of hepatic and
peritoneal involvement in sarcoidosis. Ascites was controlled
after subsequent treatment with corticosteroids and methotrexate.