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부분 뇌하수체기능저하증을 동반한 인슐린자가면역증후군 1예

DC FieldValueLanguage
dc.contributor.author김광준-
dc.contributor.author이용호-
dc.contributor.author이은직-
dc.contributor.author이현철-
dc.contributor.author임승길-
dc.contributor.author차봉수-
dc.contributor.author홍재원-
dc.date.accessioned2018-10-29T16:40:20Z-
dc.date.available2018-10-29T16:40:20Z-
dc.date.issued2009-
dc.identifier.issn2093-596X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/163851-
dc.description.abstractInsulin autoimmune syndrome is one of the rare causes of hypoglycemia, and characterized by hyperinsulinemic hypoglycemia associated with high titer of antibodies to endogenous insulin. We report a case of insulin autoimmune syndrome in a 57-year-old woman, presenting with mental changes due to hypoglycemia. She had no history of diabetes or insulin administration. The serum C-peptide level was 4.69 ng/mL and the insulin concentration was 229.55 μU/mL, when fasting plasma glucose level was 32 mg/dL. The insulin-to-glucose ratio was 7.17, while there was no radiologic evidence of insulinoma. The insulin antibody level was over 100 μU/mL, resulting in the diagnosis of insulin autoimmune syndrome. Hormonal studies revealed partial hypopituitarism and a lack of glucagon-response to hypoglycemia. Hypoglycemia disappeared with replacement of prednisolone with levothyroxine therapy. Under secretion of growth hormone and of adrenocorticotropic hormone due to hypopituitarism were associated with insufficient counterregulation to hypoglycemia. One should keep in mind that insulin autoimmune syndrome or hypopituitarism is one cause of hypoglycemia in patients with no history of diabetes, and corticosteroid can be an effective treatment for both diseases.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherKorean Endocrine Society-
dc.relation.isPartOfEndocrinology and Metabolism (대한내분비학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title부분 뇌하수체기능저하증을 동반한 인슐린자가면역증후군 1예-
dc.title.alternativeA Case of Insulin Autoimmune Syndrome in a Patient with Partial Hypopituitarism-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthor권오빈-
dc.contributor.googleauthor박은영-
dc.contributor.googleauthor윤진영-
dc.contributor.googleauthor김광준-
dc.contributor.googleauthor이용호-
dc.contributor.googleauthor홍재원-
dc.contributor.googleauthor이은직-
dc.contributor.googleauthor임승길-
dc.contributor.googleauthor이현철-
dc.contributor.googleauthor차봉수-
dc.identifier.doi10.3803/jkes.2009.24.4.281-
dc.contributor.localIdA00317-
dc.contributor.localIdA00317-
dc.contributor.localIdA02989-
dc.contributor.localIdA03050-
dc.contributor.localIdA03301-
dc.contributor.localIdA03375-
dc.contributor.localIdA03996-
dc.contributor.localIdA04427-
dc.relation.journalcodeJ00773-
dc.identifier.eissn2093-5978-
dc.subject.keywordcorticosteroid-
dc.subject.keywordhypopituitarism-
dc.subject.keywordinsulin autoimmune syndrome-
dc.contributor.alternativeNameKim, Kwang Joon-
dc.contributor.alternativeNameLee, Yong Ho-
dc.contributor.alternativeNameLee, Eun Jig-
dc.contributor.alternativeNameLee, Hyun Chul-
dc.contributor.alternativeNameLim, Sung Kil-
dc.contributor.alternativeNameCha, Bong Soo-
dc.contributor.alternativeNameHong, Jae Won-
dc.contributor.affiliatedAuthor김광준-
dc.contributor.affiliatedAuthor이용호-
dc.contributor.affiliatedAuthor이은직-
dc.contributor.affiliatedAuthor이현철-
dc.contributor.affiliatedAuthor임승길-
dc.contributor.affiliatedAuthor차봉수-
dc.contributor.affiliatedAuthor홍재원-
dc.citation.volume24-
dc.citation.number4-
dc.citation.startPage281-
dc.citation.endPage286-
dc.identifier.bibliographicCitationEndocrinology and Metabolism (대한내분비학회지), Vol.24(4) : 281-286, 2009-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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