Cited 24 times in
Predictive Nomogram for Recurrence of Stage I Colorectal Cancer After Curative Resection
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김기열 | - |
dc.contributor.author | 김남규 | - |
dc.contributor.author | 범승훈 | - |
dc.contributor.author | 신상준 | - |
dc.contributor.author | 안중배 | - |
dc.contributor.author | 정민규 | - |
dc.date.accessioned | 2018-10-11T08:54:21Z | - |
dc.date.available | 2018-10-11T08:54:21Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1533-0028 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/163451 | - |
dc.description.abstract | BACKGROUND: Patients with stage I colorectal cancer (CRC) have excellent prognosis after curative surgery. However, approximately 5% to 10% of patients experience recurrence and have a poor prognosis. Because the incidence of stage I CRC is increasing with active screening programs worldwide, a more accurate and easy-to-use predictive tool for recurrence is becoming more important. This study aimed to develop a predictive nomogram for recurrence in stage I CRC. PATIENTS AND METHODS: A total of 1538 patients who underwent curative surgery for stage I CRC were enrolled. Predictive factors for recurrence were determined by multivariate Cox regression model and were used to develop a predictive nomogram. This model was internally validated, and performance was evaluated through calibration plots. RESULTS: The cumulative recurrence rate at 5 years after surgery for stage I CRC was 5.3%. In multivariate Cox analysis, independent predictors of recurrence were tumor location at rectum, pT2 stage, and presence of lymphovascular invasion. The 5-year recurrence rate was significantly different depending on the number of risk factors (0.7% for 0, 5.8% for 1, and 9.7% for ≥ 2 risk factors). On this basis, a nomogram for recurrence-free survival was developed and internally validated. The concordance index of the nomogram was 0.71, and the performance was acceptable. CONCLUSION: We developed and internally validated a nomogram that can predict postoperative recurrence in stage I CRC patients. This nomogram may be used to more accurately stratify the risk of recurrence and to perform personalized postoperative surveillance in stage I CRC patients. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | United States | - |
dc.publisher | 1938-0674 | - |
dc.relation.isPartOf | CLINICAL COLORECTAL CANCER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Predictive Nomogram for Recurrence of Stage I Colorectal Cancer After Curative Resection | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry | - |
dc.contributor.department | Others | - |
dc.contributor.googleauthor | Chan Kim | - |
dc.contributor.googleauthor | Woo Ram Kim | - |
dc.contributor.googleauthor | Ki-Yeol Kim | - |
dc.contributor.googleauthor | Hong Jae Chon | - |
dc.contributor.googleauthor | Seung Hoon Beom | - |
dc.contributor.googleauthor | Hyojoong Kim | - |
dc.contributor.googleauthor | Minkyu Jung | - |
dc.contributor.googleauthor | Sang Joon Shin | - |
dc.contributor.googleauthor | Nam Kyu Kim | - |
dc.contributor.googleauthor | Joong Bae Ahn | - |
dc.identifier.doi | 10.1016/j.clcc.2018.03.011 | - |
dc.contributor.localId | A00337 | - |
dc.contributor.localId | A00353 | - |
dc.contributor.localId | A04581 | - |
dc.contributor.localId | A02105 | - |
dc.contributor.localId | A02262 | - |
dc.contributor.localId | A03606 | - |
dc.relation.journalcode | J03468 | - |
dc.identifier.eissn | 1938-0674 | - |
dc.identifier.pmid | 29661621 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S153300281730511X | - |
dc.subject.keyword | Colorectal Cancer | - |
dc.subject.keyword | Nomogram | - |
dc.subject.keyword | Prognosis | - |
dc.subject.keyword | Recurrence | - |
dc.subject.keyword | Stage I | - |
dc.contributor.alternativeName | Kim, Ki Yeol | - |
dc.contributor.alternativeName | Kim, Nam Kyu | - |
dc.contributor.alternativeName | Beum, Seung Hoon | - |
dc.contributor.alternativeName | Shin, Sang Joon | - |
dc.contributor.alternativeName | Ahn, Joong Bae | - |
dc.contributor.alternativeName | Jung, Min Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Ki Yeol | - |
dc.contributor.affiliatedAuthor | Kim, Nam Kyu | - |
dc.contributor.affiliatedAuthor | Beum, Seung Hoon | - |
dc.contributor.affiliatedAuthor | Shin, Sang Joon | - |
dc.contributor.affiliatedAuthor | Ahn, Joong Bae | - |
dc.contributor.affiliatedAuthor | Jung, Min Kyu | - |
dc.citation.volume | 17 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | e513 | - |
dc.citation.endPage | e518 | - |
dc.identifier.bibliographicCitation | CLINICAL COLORECTAL CANCER, Vol.17(3) : e513-e518, 2018 | - |
dc.identifier.rimsid | 60400 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.